AUTHOR=Li Ziyuan , Luan Shuyi , Yan LongGang , Xie Chengyun , Lian Zhengjie , Yang Mingmao , Mei Minmin , Lin Pengfei , Wang Aihua , Jin Yaping TITLE=Effect of Double-Ovsynch and Presynch-Ovsynch on postpartum ovarian cysts and inactive ovary in high-yielding dairy cows JOURNAL=Frontiers in Veterinary Science VOLUME=Volume 11 - 2024 YEAR=2024 URL=https://www.frontiersin.org/journals/veterinary-science/articles/10.3389/fvets.2024.1348734 DOI=10.3389/fvets.2024.1348734 ISSN=2297-1769 ABSTRACT=Optimizing the management of dairy cattle reproduction can reduce postpartum ovarian disease in high-yielding dairy cows and thus enhance ranch economic benefit. The hypothesis of this study was that the Double-Ovsynch (DO) protocol in high-producing dairy cows would result in a lower incidence of follicular cysts but a higher incidence of luteal cysts compared to those undergoing the Presynch-Ovsynch (PS) protocol. In this experiment, 384 cows (204 primiparous and 180 multiparous) were allocated to the DO group, which followed the protocol:GnRH-7d-PGF2α-3d-GnRH-7d-Ovsynch-56h(GnRH-7d-PGF2α-56h-GnRH-16hTAI), starting on 39±3 days in milk (DIM). Additionally, 359 cows (176 primiparous and 183 multiparous)