ORIGINAL RESEARCH article
Front. Vet. Sci.
Sec. Veterinary Infectious Diseases
This article is part of the Research TopicReviews in Pathology of Infectious Diseases - Volume IIView all 11 articles
Genomic Sequencing and Analysis of New Variants of Enzootic Nasal Tumor Virus Type Revealed Recombination Events Between Different Sublineages in China
Provisionally accepted
- 1Guizhou Institute of Animal Husbandry and Veterinary Medicine, Guiyang, China
- 2Guizhou University, Guiyang, China
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In recent years, cases of Enzootic Nasal Tumor Virus Type 2 (ENTV-2) infection have increased and become widespread in several provinces of China. In this study, we report the first complete genome of ENTV-2 from Guizhou in southwestern China. The full genome of an emerging ENTV-2 isolate (named GZZY1) was sequenced at 7504 bp. Phylogenetic analysis showed that GZZY1 belongs to a potential sublineage, 1.6. Additionally, recombination analysis indicated that GZZY1 might be a recombinant variant derived from sublineages 1.2 and 1.5, with the recombination region in the gag and env genes. In summary, we sequenced and analyzed the complete genome of a potential ENTV-2 recombinant, which may help improve our understanding of the genetic variation and evolution of ENTV-2 in China.
Keywords: enzootic nasal tumor virus type 2, Genomic Analysis, Goat, phylogenetic analysis, recombination
Received: 11 Jul 2025; Accepted: 08 Dec 2025.
Copyright: © 2025 Pan, Yang, Li, Xu, Xu and Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
* Correspondence: Yong Pan
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