https://www.frontiersin.org/journals/veterinary-science RSS Feed for Frontiers in Veterinary Science | New and Recent Articles en-us Frontiers Feed Generator,version:1 2026-05-04T03:58:21.489+00:00 60 https://www.frontiersin.org/articles/10.3389/fvets.2026.1791118 https://www.frontiersin.org/articles/10.3389/fvets.2026.1791118 2026-05-01T00:00:00Z Review Lebogang OthusitseTshephang I. KabeloKaone A. NkweLaToya SeokeElliot M. FanaKebaneilwe Lebani https://www.frontiersin.org/articles/10.3389/fvets.2026.1755813 https://www.frontiersin.org/articles/10.3389/fvets.2026.1755813 2026-05-01T00:00:00Z Original Research Dunia Yisela Trujillo PisoYeli Camila Van-Arcken AguilarMónica Yamile Padilla BarretoMaría del Pilar Sánchez Bonilla https://www.frontiersin.org/articles/10.3389/fvets.2026.1727080 https://www.frontiersin.org/articles/10.3389/fvets.2026.1727080 2026-05-01T00:00:00Z Review Rajshree VidyashankarSubhash Verma https://www.frontiersin.org/articles/10.3389/fvets.2026.1798131 https://www.frontiersin.org/articles/10.3389/fvets.2026.1798131 2026-05-01T00:00:00Z Original Research Ye XuSiyu YangSiling DingTing XuLike ZhuWeiming XiaoJian GeFeng Guan https://www.frontiersin.org/articles/10.3389/fvets.2026.1843100 https://www.frontiersin.org/articles/10.3389/fvets.2026.1843100 2026-05-01T00:00:00Z Review Guanglong WangSuo Zhang https://www.frontiersin.org/articles/10.3389/fvets.2026.1788257 https://www.frontiersin.org/articles/10.3389/fvets.2026.1788257 2026-05-01T00:00:00Z Original Research Zhi H. HsuAlex M. LynchRonald H. LiBernie HansenYu Ueda  0.99). The mortality rate of animals with AKI was 64% (16/25) while those without AKI was 50.7% (36/71) (p = 0.35). AKI development was not significantly associated with the survival to discharge rate, while SpO2 measured before (p = 0.01) and after initiation of MV (p = 0.0079) and duration of hospitalization (p < 0.0001) were significantly associated with the survival to discharge rate. In multivariable logistic regression analysis, age, baseline serum creatinine, congestive heart failure status, and duration of MV and hospitalization were not independently associated with AKI development.ConclusionAKI was common in animals managed with MV. However, the development of AKI was not significantly associated with the survival to discharge rate in this cohort.]]> https://www.frontiersin.org/articles/10.3389/fvets.2026.1734152 https://www.frontiersin.org/articles/10.3389/fvets.2026.1734152 2026-04-30T00:00:00Z Original Research Li HanYuetao LiHaocheng ZhangYidan WangJinqing JiangRenfeng LiGuoying FanYanhong CuiYongqiang WangZiliang WangChangzhong LiuWen Chen https://www.frontiersin.org/articles/10.3389/fvets.2026.1774322 https://www.frontiersin.org/articles/10.3389/fvets.2026.1774322 2026-04-30T00:00:00Z Review Lun SunXin WangYong LongXu WangXinran NiuHuijie LiNittaya TaethaisongWeerada MeethipSiwaporn PaengkoumPramote Paengkoum https://www.frontiersin.org/articles/10.3389/fvets.2026.1611532 https://www.frontiersin.org/articles/10.3389/fvets.2026.1611532 2026-04-30T00:00:00Z Original Research Yangyang MaXiaohui PengYuting LinTiantian XiaQianqian PanYuhang WuMingjing CuiShuaifeng ShenFugui FangYunsheng LiZubing CaoYunhai ZhangTong Yu https://www.frontiersin.org/articles/10.3389/fvets.2026.1798164 https://www.frontiersin.org/articles/10.3389/fvets.2026.1798164 2026-04-30T00:00:00Z Case Report Marlene SickingerDaniela FarkeMeike L. SchmidtMartin J. Schmidt https://www.frontiersin.org/articles/10.3389/fvets.2026.1813283 https://www.frontiersin.org/articles/10.3389/fvets.2026.1813283 2026-04-30T00:00:00Z Original Research Viktoria SiewertLouisa BierbaumMelanie GleskeCarolin MundingerRupert PalmeSylvia KaiserNorbert SachserS. Helene Richter https://www.frontiersin.org/articles/10.3389/fvets.2026.1801528 https://www.frontiersin.org/articles/10.3389/fvets.2026.1801528 2026-04-30T00:00:00Z Original Research Bin JiaYan TianChanghong GaoYaqi ChangZexin ZhangYuxi SongCheng XiaYongli QuWei Yang  2%) were used to evaluate the factors related to BA metabolism. In vitro, hepatocytes isolated from three healthy female calves were exposed to either 1.2 mM FFAs or kept as controls to simulate metabolic distress. Subsequently, hepatocytes were treated with either 5 µM of the FXR activator GW4064 or 5 µM of the FXR inhibitor (Z)-guggulsterone with or without the addition of 1.2 mM FFAs.ResultsOur findings indicate that both in vivo and in vitro exposure to FFAs was associated with increased mRNA and protein abundance of bile acid synthesis-related factors (CYP7A1, CYP8B1) and mRNA expression of CYP7B1. Conversely, the expression of BA synthesis-related factors (FXR, CYP27A1) and BA transporters (ABCC2, ABCB11) were diminished in fatty liver cows compared to controls. Furthermore, compared to the control group, fatty acid synthesis-related factors (SREBF1, ACC1, FASN), a mitochondrial dysfunction marker (VDAC1), and oxidative stress indicators (ROS, H2O2) were upregulated in the FFA group. Additionally, cholesterol synthesis-related genes (SREBF2, HMGCR) were lower in the FFA group compared to the control group. Notably, compared to the FFA group, the GW4064 + FFA group showed reduced expression of CYP7A1, CYP8B1, CYP27A1, CYP7B1, SREBF1, ACC1, FASN, and VDAC1, along with decreased TAG, ROS, and H2O2 in hepatocytes. Conversely, the expression of FXR, SREBF2, HMGCR, ABCC2, and ABCB11 was higher in the GW4064 + FFA group compared to the FFA group. Furthermore, the application of the FXR inhibitor (Z)-guggulsterone yielded results that were contrary those observed with GW4064.DiscussionOverall, our data suggest that FXR activation by GW4064 effectively attenuated high FFA-induced BA and lipid accumulation in calf hepatocytes, which ultimately alleviated hepatocyte oxidative damage.]]> https://www.frontiersin.org/articles/10.3389/fvets.2026.1839256 https://www.frontiersin.org/articles/10.3389/fvets.2026.1839256 2026-04-30T00:00:00Z Original Research Yongliang ZhangJunmei ZhangLeilei SunQing LiWenbo SongMingguang ZhouGaoyuan XuXibiao TangHuanchun ChenYunfeng Song https://www.frontiersin.org/articles/10.3389/fvets.2026.1789173 https://www.frontiersin.org/articles/10.3389/fvets.2026.1789173 2026-04-30T00:00:00Z Original Research Juliano L. GonçalvesAmanda T. F. SilvaKarla VascoCara I. RobisonShannon D. ManningLixin ZhangBo NorbyRinosh ManiPamela L. Ruegg https://www.frontiersin.org/articles/10.3389/fvets.2026.1778331 https://www.frontiersin.org/articles/10.3389/fvets.2026.1778331 2026-04-30T00:00:00Z Review Kyle L. GrangerCody I. RiffeSøren R. BoysenCharles T. Talbot https://www.frontiersin.org/articles/10.3389/fvets.2026.1812243 https://www.frontiersin.org/articles/10.3389/fvets.2026.1812243 2026-04-30T00:00:00Z Original Research Aleksandra UzelacKatarina BrekaAleksandra PenezićIlija PantelićMilica KuručkiNeda BogdanovićTijana KukurićNikola BetićJelena KaranovićIvana KlunDuško Ćirović https://www.frontiersin.org/articles/10.3389/fvets.2026.1853921 https://www.frontiersin.org/articles/10.3389/fvets.2026.1853921 2026-04-30T00:00:00Z Correction Ecaterina SemzenisiRomelia PopAndrada NegoescuLucia BelAlexandra CreţIrina ConstantinClaudiu-Nicusor IonicaSorana CatoiIbrahima Mamadou SallAlexandu-Flaviu Tǎbǎran https://www.frontiersin.org/articles/10.3389/fvets.2026.1779067 https://www.frontiersin.org/articles/10.3389/fvets.2026.1779067 2026-04-30T00:00:00Z Case Report Dries K. M. VercoutereLucinda L. Van SteeErik A. W. S. WeertsBjörn P. Meij 50% dorsal spinal cord compression and were isointense to the spinal cord on T1-weighted images and hypointense on T2–weighted images. Cytology prior to surgical intervention was performed in one case, confirming sarcoma diagnosis, and both affected cats underwent a dorsal laminectomy procedure, involving the removal of the affected spinous process and lamina. Histopathology was performed for both patients and confirmed giant cell osteosarcoma in both cases and additional features consistent with the telangiectatic subtype of osteosarcoma in one case. Post-operative recovery included initial resolving of presenting clinical signs, though both cats ultimately experienced recurrent neurological deterioration consistent with local tumor recurrence, leading to euthanasia. These cases illustrate that spinal giant cell osteosarcoma should be considered in cats with progressive myelopathy. They demonstrate that surgical decompression alone can provide substantial neurological improvement, with the potential for medium-term stability or remission. As local tumor recurrence caused eventual relapse of clinical signs, improving pre-, and intraoperative tumor margin identification and applying adjuvant treatments may improve longterm outcome, and should be investigated in future cases.]]> https://www.frontiersin.org/articles/10.3389/fvets.2026.1779996 https://www.frontiersin.org/articles/10.3389/fvets.2026.1779996 2026-04-30T00:00:00Z Case Report Mihyun ChoiYongsun KimKyuseok ChoiJihun WonNamsoon Lee https://www.frontiersin.org/articles/10.3389/fvets.2026.1813360 https://www.frontiersin.org/articles/10.3389/fvets.2026.1813360 2026-04-29T00:00:00Z Case Report Ursa Lampreht TratarTanja SvaraMaja CemazarGregor SersaNatasa Tozon Mask