About this Research Topic
Emerging evidence has shown that abnormal neuronal metabolism and overactive inflammation contribute significantly to the initiation and progression of ocular diseases. Retinal neurons metabolize rapidly, and the retinal vascular network is tightly regulated to meet the oxygen and nutrient demands of the neurons. However, the regulation of retinal metabolism and inflammation is still poorly understood. Expanding knowledge in these pathways may lead to identification of new drug targets for prevention and treatment of retinal vascular abnormalities.
Scope: The present Research Topic is intended to be a collection of new pathological evidence and novel therapeutic targets regarding the prevention and treatment of retinal neurovascular disorders.
Details for Authors: Original Research articles and Reviews will be preferred. Themes encompass:
1. Discovering new pathogenesis of abnormal retinal neurovascular dysfunction with a focus on abnormal metabolism or unregulated inflammatory responses.
2. Highlighting innovative drug development and delivery.
3. Evaluating the efficacy and safety of the potential drug targets.
Keywords: Neuron, neovascularization, vascular endothelial growth factor (VEGF), blood-retinal barrier, drug delivery
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.