About this Research Topic
Over the last few decades, epidemiological studies have revealed a rising prevalence of infertility worldwide. According to World Health Organization reports, approximately 25% of couples are experiencing infertility in developing countries. Growing evidence supports that extensive use of chemicals, particularly Endocrine Disrupting Chemicals (EDCs), are the potential causes of infertility. Exposure to EDCs in everyday life may lead to long term persistence in the biological fluids, which manipulates normal hormonal homeostasis and causes detrimental health effects, including reproductive abnormalities/infertility.
This Research Topic aims to provide an up-to-date summary of the all aspects of endocrine disruptors and (in)fertility perspectives in humans and in model organisms. We welcome reviews, original research articles, technical notes, and commentaries that are related to genomics, epigenomics, proteomics, or metabolomics views of EDC-mediated reproductive perturbations.
Potential topics include, but are not limited to:
• Effects of EDCs on germ cells/reproductive tract/fertility.
• Developing novel methods/tools to better understand how EDCs affects (in)fertility.
• Examining the long- and short-term effects of EDC exposure on (in)fertility.
• Discovery of EDC biomarkers and their clinical significance for infertility.
• Developing possible prevention/treatment strategies to minimize EDC-induced infertility.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.