About this Research Topic
Chiral analysis is of great importance to pharmaceutical sciences, biology and chemistry. Analysis of a chiral sample concerns the determination of enantiomeric excess and total concentration of all the enantiomers. Beyond traditional chromatographic and electrophoretic techniques, chiral sensors represent a wide series of chiral analysis methods which possess several advantages including independence from instruments, low cost, and rapid and in situ analysis. So far, chiral sensors have been developed based on transduction of colorimetric, fluorescent, electrochemical, oscillation, and other signals.
There are several aspects of chiral sensors that need to be improved: (1) the capability of a single chiral probe to determine an unknown sample with both enantiomeric excess and total concentration; (2) the capability of in vivo or intracellular imaging of chiral biomolecules (such as D-amino acids in the brain); (3) the enantioselectivity of current chiral sensors to fulfill practical applications; and (4) the development of more chiral array sensing methods for complex sample analysis.
In this Research Topic, authors are welcome to submit manuscripts describing innovative methods of chiral sensing or novel chiral sensor development including, but not limited to, the following:
• Colorimetric chiral sensors
• Fluorescent chiral sensors
• Electrochemical chiral sensors
• Chiral sensing/imaging within living cells and in vivo with chiral probes
• Comprehensive chiral analysis with a single chiral probe
• High-throughput chiral sensing
• Chiral array sensing
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.