Research Topic

Meaningful Cases of Primary Immunodeficiencies, Volume III

About this Research Topic

Following on from the success of Volume I and Volume II of Meaningful Cases of Primary Immunodeficiencies, we are pleased to launch Volume III of this Research Topic. Our understanding of primary immunodeficiency is enriched by cases of extraordinary patients who present to pediatricians and pediatric clinics. Atypical presentations of these genetic disorders of the immune system foster broadening of our recognition and understanding of the diseases themselves while providing new insights pertaining to the human immune system and basic immunologic mechanisms. Examples include specific infections, novel types of immune dysregulation, and unusual immunologic phenotypes. Often, the first step in the process appears in the form of a detailed and instructive case report.

In this Research Topic, we welcome informative Case Reports that expand our current knowledge regarding primary Immunodeficiencies. Reports should include full details of the cases, including relevant full clinical imagery, to capture the breadth of data that might otherwise be lost in shortened or abbreviated formats elsewhere.


Keywords: Primary immunodeficiency, immune dysregulation, case report, testing, outcome


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Following on from the success of Volume I and Volume II of Meaningful Cases of Primary Immunodeficiencies, we are pleased to launch Volume III of this Research Topic. Our understanding of primary immunodeficiency is enriched by cases of extraordinary patients who present to pediatricians and pediatric clinics. Atypical presentations of these genetic disorders of the immune system foster broadening of our recognition and understanding of the diseases themselves while providing new insights pertaining to the human immune system and basic immunologic mechanisms. Examples include specific infections, novel types of immune dysregulation, and unusual immunologic phenotypes. Often, the first step in the process appears in the form of a detailed and instructive case report.

In this Research Topic, we welcome informative Case Reports that expand our current knowledge regarding primary Immunodeficiencies. Reports should include full details of the cases, including relevant full clinical imagery, to capture the breadth of data that might otherwise be lost in shortened or abbreviated formats elsewhere.


Keywords: Primary immunodeficiency, immune dysregulation, case report, testing, outcome


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

06 July 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

06 July 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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