Research Topic

Peri-Implantitis: A Growing Health Issue

About this Research Topic

Tooth loss is one of the main complications of periodontitis. Dental implants are commonly used worldwide to replace missing teeth with a high rate of long-term survival. Over the last decade, an increasing rate of biological complications, mucositis and peri-implantitis, has been observed. Such diseases of infectious origin are the main cause of implant loss as they are characterized by the inflammation and destruction of peri-implant tissues.

The management of mucositis and peri-implantitis is challenging. Several non-surgical and surgical protocols have been proposed and evaluated so far. However, data related to the treatment outcomes and their long-term stability remain contradictory emphasizing the need of a better characterization of the biological processes involved in peri-implant diseases, development and of new therapeutic approaches.

This Research Topic aims to highlight the latest research associated with the development of promising peri-implant therapeutics. We invite researchers to contribute original research, review articles, basic and clinical studies focusing on the epidemiology, pathogenesis and treatment of peri-implant diseases.

Potential topics include but are not limited to the following:

• Basic molecular and cellular mechanisms involved in peri-implantitis development
• Identification and validation of novel agents that modulate inflammatory responses at peri-implant level
• Identification and validation of novel molecules and biomarkers critical for peri-implantitis early detection
• Innovative peri-implantitis treatment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Tooth loss is one of the main complications of periodontitis. Dental implants are commonly used worldwide to replace missing teeth with a high rate of long-term survival. Over the last decade, an increasing rate of biological complications, mucositis and peri-implantitis, has been observed. Such diseases of infectious origin are the main cause of implant loss as they are characterized by the inflammation and destruction of peri-implant tissues.

The management of mucositis and peri-implantitis is challenging. Several non-surgical and surgical protocols have been proposed and evaluated so far. However, data related to the treatment outcomes and their long-term stability remain contradictory emphasizing the need of a better characterization of the biological processes involved in peri-implant diseases, development and of new therapeutic approaches.

This Research Topic aims to highlight the latest research associated with the development of promising peri-implant therapeutics. We invite researchers to contribute original research, review articles, basic and clinical studies focusing on the epidemiology, pathogenesis and treatment of peri-implant diseases.

Potential topics include but are not limited to the following:

• Basic molecular and cellular mechanisms involved in peri-implantitis development
• Identification and validation of novel agents that modulate inflammatory responses at peri-implant level
• Identification and validation of novel molecules and biomarkers critical for peri-implantitis early detection
• Innovative peri-implantitis treatment


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Topic Editors

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Submission Deadlines

30 September 2021 Abstract
30 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

30 September 2021 Abstract
30 December 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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