Research Topic

Advances in Label-free Biosensors for the Detection of Cancer Biomarkers

About this Research Topic

Cancer is the second main cause of death for humans around the world. The chance for successful treatment increases when cancer is diagnosed in its early stages. Developing accurate and sensitive techniques for early stage diagnosis of cancer is vital for improved treatment outcomes. However, most of the currently used techniques suffer from limitations, such as high cost, long analysis time, false-positive/negative results, low-sensitivity and also usually provide only qualitative results.

Thus, the development of new analytical methods with simple, low-cost, rapid, accurate and specific features is of great importance in improving cancer diagnosis, without the need for expensive clinical chemistry laboratories. In this regard, development of label-free approaches that do not require pre-treatment of samples (in biological environments such as whole blood, whole plasma, whole serum, saliva, exhaled breath condensate, etc.) as the first step of cancer diagnosis or screening is of great importance.

The design and testing of pre-treatment-free approaches for early stage detection of cancer biomarkers is the subject of this Research Topic.

We invite submissions that include Original Research and Review articles. The scope of the Research Topic covers the following areas:

-New advanced analytical methods for cancer biomarker detection
-Microfluidic systems and microfluidic droplets for cancer biomarker detection
-Electrochemical, spectroscopic methods for the detection of cancer biomarkers. Note that all methods should be applicable to biological environments such as whole blood, whole plasma, whole serum, saliva, exhaled breath condensate (EBC), etc.


Keywords: cancer, biomarker, early stage detection, label-free, biosensor


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Cancer is the second main cause of death for humans around the world. The chance for successful treatment increases when cancer is diagnosed in its early stages. Developing accurate and sensitive techniques for early stage diagnosis of cancer is vital for improved treatment outcomes. However, most of the currently used techniques suffer from limitations, such as high cost, long analysis time, false-positive/negative results, low-sensitivity and also usually provide only qualitative results.

Thus, the development of new analytical methods with simple, low-cost, rapid, accurate and specific features is of great importance in improving cancer diagnosis, without the need for expensive clinical chemistry laboratories. In this regard, development of label-free approaches that do not require pre-treatment of samples (in biological environments such as whole blood, whole plasma, whole serum, saliva, exhaled breath condensate, etc.) as the first step of cancer diagnosis or screening is of great importance.

The design and testing of pre-treatment-free approaches for early stage detection of cancer biomarkers is the subject of this Research Topic.

We invite submissions that include Original Research and Review articles. The scope of the Research Topic covers the following areas:

-New advanced analytical methods for cancer biomarker detection
-Microfluidic systems and microfluidic droplets for cancer biomarker detection
-Electrochemical, spectroscopic methods for the detection of cancer biomarkers. Note that all methods should be applicable to biological environments such as whole blood, whole plasma, whole serum, saliva, exhaled breath condensate (EBC), etc.


Keywords: cancer, biomarker, early stage detection, label-free, biosensor


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

18 June 2020 Abstract
18 December 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

18 June 2020 Abstract
18 December 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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