About this Research Topic
Gender dysphoria (GD) is a state of distress caused by incongruence between a person’s gender identity and their assigned sex at birth. Gender identity reflects a complex interplay of biological, environmental, and cultural factors and the origin of GD could be multifactorial: in addition to the psychological and socio-cultural factors, some interesting endocrinological hypotheses have emerged. Gender affirming hormone therapy has the main goal of alleviating GD by replacing endogenous hormones with those of the asserted/expressed gender.
The aim of this Research Topic is to provide a review of the published literature on the multidisciplinary approach to gender dysphoria during the lifespan: etiopatogenetic hypotheses, diagnosis, psychological and endocrinological management, psychiatric issues, quality of life and sexual function, gender-confirming surgery.
A specific part will be dedicated to the known hypotheses of gender dysphoria genesis. How sexual hormones influence gender identity development will be included. Particular issues such as fertility preservation, cardiovascular risk, cancer risk, and social aspects (e.g sport participation and competitive sport policies) will be included.
This Research Topic will provide all professionals involved in the management of gender dysphoria in pediatric age, adulthood, and aging an up-to-date and comprehensive literature review useful in their clinical practice. The Research Topic will consist of a number of short reviews focusing on the most interesting and relevant articles published recently in the field.
Themes of interest include the following:
• Determinants of gender identity development
• Gender dysphoria: definition and diagnosis
• Psychological management of gender dysphoria
• Gender affirming treatment in pediatric and adult patients
• Gender-confirming surgery
• Quality of life and sexual function in transgender persons
• Particular topics mentioned prior
Keywords: Gender dysphoria, transgender, transsexual, sex steroids, sexual function
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