About this Research Topic
Biomaterials with adequate physical and mechanical properties are non-toxic, biocompatible, non-teratogenic, and non-immunogenic synthetic substances that are widely used in therapeutic fields to augment or replace natural bodily functions. In the current era, the emerging research interests combine the information and expertise from different fields like Materials Science, Life Sciences, and Chemistry to understand the properties of biomaterials and their interaction with the body. The selection of biomaterials is closely related to the proposed application in soft/hard tissues. The use of nanotechnology is under consideration in improving the properties of conventional biomaterials such as cell adhesion, proliferation, and differentiation. The nanomaterials are introducing possibilities in tailoring the bio-implants chemistry and structure with appropriate control. The significant potential of nanophase biomaterials for regenerative medicine/tissue engineering is motivating researchers to develop advanced implant fabrication techniques to design the physical, chemical, and biological properties of implants. The manipulation of the physicochemical environment, as well as cellular event monitoring at the molecular level, can offer new capabilities in terms of reduced healing time, faster organ formation, and rapid functional recovery.
Biomaterials are a big technical challenge but despite this, they continue to be one of the fastest-growing research fields of the present time. These synthetic structures have an enormous impact on the treatment of injury/disease throughout the body. The performance of biomaterials is evaluated based on their properties as well as their capabilities to cope with the surrounding biological environment. This Research Topic aims to emphasize the development, manufacturing, and applications of nano-biomaterials. The optimization studies for nano-biomaterials and implant characteristics, keeping in view safe medical practices, are also welcomed. This issue covers research areas ranging from nano-biomaterials characterization to in vivo and in vitro testing of their biological performance assessment. Besides the design, selection, and synthesis of nano-biomaterials, the complexity of the cell and tissue reactions to these materials will also be covered. The issue will provide the opportunity to cover both fundamental and applied research on nano-biomaterials to the broader community of researchers/academicians/practitioners working in this scientific domain.
The scope of this issue covers the wide range of chemical, physical, and biological sciences for the design of nano-biomaterials and their application for regenerative medicine/tissue engineering. In this topic issue, we would like to invite significant advancements in the related areas of nano-biomaterials to report work in Frontiers in Nanotechnology/Biomedical Nanotechnology.
The topics of interest include, but not limited to:
• Biomaterials for regenerative medicine/tissue engineering
• Nanotechnology-based surface modification of biomaterials
• Smart nano-biomaterials design for regenerative medicine/tissue engineering
• 3D-printed functional nano-biomaterials for regenerative medicine/tissue engineering
• Nano-biomaterial and stem cell interactions
• Nano-bioengineered scaffolds for stem cell applications
• Nanotechnology and novel fabrication techniques for scaffolds
• Biomechanics of nano-biomaterials and medical devices
The papers focusing on clinical and translational research do not fall within the scope of this section. The original contributions in the form of research articles, reviews, mini-reviews, corrections and methods will be accepted.
Keywords: Biomaterials, Biocompatible, Tissue Engineering, Regenerative Medicine, nano Biomaterials
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.