Research Topic

Genetic and Immunologic Response in Kawasaki Disease

About this Research Topic

Kawasaki Disease (KD) is a systemic vasculitis with unknown etiology until now. Immune, infectious or cardiologic diseases are all responsible for KD but not specific. KD affects mostly on children with age less than 5 years-old and intravenous immunoglobulin can provide good treatment response in the past decade. Coronary artery lesions are the main complication of KD and may have a life-long impact. Genetic or immunologic factors may play an essential role in KD.

There are more than 5,000 publications about KD from the PubMed database search, and most of them showed association with genes or immune response. This Research Topic welcomes articles of KD specific on the section of genetics and immune response from different nations or different areas that come from all over the world with the aim to get the immunopathogenic findings more clearly. The goal of this Research Topic is to provide more information about genetic or immunologic findings and even put them together to figure out the possibility of the etiology of KD from articles collected.

• original or review articles are preferred
• immune response including B cell, T cell, macarphage, complement, phagocyte
• genetic study should provide functional study or function analysis, (SNP studies will not be accepted)
• meta-analysis of one SNP will be accepted


Keywords: kawasaki disease, gene, immune


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Kawasaki Disease (KD) is a systemic vasculitis with unknown etiology until now. Immune, infectious or cardiologic diseases are all responsible for KD but not specific. KD affects mostly on children with age less than 5 years-old and intravenous immunoglobulin can provide good treatment response in the past decade. Coronary artery lesions are the main complication of KD and may have a life-long impact. Genetic or immunologic factors may play an essential role in KD.

There are more than 5,000 publications about KD from the PubMed database search, and most of them showed association with genes or immune response. This Research Topic welcomes articles of KD specific on the section of genetics and immune response from different nations or different areas that come from all over the world with the aim to get the immunopathogenic findings more clearly. The goal of this Research Topic is to provide more information about genetic or immunologic findings and even put them together to figure out the possibility of the etiology of KD from articles collected.

• original or review articles are preferred
• immune response including B cell, T cell, macarphage, complement, phagocyte
• genetic study should provide functional study or function analysis, (SNP studies will not be accepted)
• meta-analysis of one SNP will be accepted


Keywords: kawasaki disease, gene, immune


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

04 July 2020 Abstract
01 November 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

04 July 2020 Abstract
01 November 2020 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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