About this Research Topic
Kawasaki Disease (KD) is a systemic vasculitis with unknown etiology until now. Immune, infectious or cardiologic diseases are all responsible for KD but not specific. KD affects mostly on children with age less than 5 years-old and intravenous immunoglobulin can provide good treatment response in the past decade. Coronary artery lesions are the main complication of KD and may have a life-long impact. Genetic or immunologic factors may play an essential role in KD.
There are more than 5,000 publications about KD from the PubMed database search, and most of them showed association with genes or immune response. This Research Topic welcomes articles of KD specific on the section of genetics and immune response from different nations or different areas that come from all over the world with the aim to get the immunopathogenic findings more clearly. The goal of this Research Topic is to provide more information about genetic or immunologic findings and even put them together to figure out the possibility of the etiology of KD from articles collected.
• original or review articles are preferred
• immune response including B cell, T cell, macarphage, complement, phagocyte
• genetic study should provide functional study or function analysis, (SNP studies will not be accepted)
• meta-analysis of one SNP will be accepted
• relationship between Kawasaki disease (KD) and COVID-19 infection or KD-like multi-system inflammatory syndrome in children (MISC)
Keywords: kawasaki disease, gene, immune
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