Research Topic

Diagnostics in Neuropathic Pain

About this Research Topic

Symptoms of neuropathic pain are present in approximately 5% of the Western population and are a large burden to patients and their environment. On top of symptoms of neuropathic pain, the majority of patients also experience other symptoms such as alterations in mood, anxiety, sleep disorder and neurocognitive impairment. Treatment remains challenging due to the lack of adequate efficacy of currently available treatment options. Opportunities for future improvement of treatment efficacy lie in the implementation of personalized medicine by improvement and utilization of sensitive diagnostic tools to provide pain therapies based on patient characteristics rather than on underlying disease. Increasing knowledge on causes and consequences of individual disease patterns, including psychological factors, is necessary to improve accurate individualized pain management.

The aims of the current Research Topic are to (1) provide state-of-the art insights and knowledge on signs and symptoms of neuropathic pain; (2) present (novel) diagnostics and analyses techniques that aid in the identification of neuropathic pain patients; and (3) give an overview of a possible patient classification system to identify patient subgroups and guide appropriate treatment regimens. Both human and animal studies are considered for publication.


Keywords: Neuropathic Pain, Quantitative Sensory Testing, Phenotyping, Subgroup Analyses, Diagnostics


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Symptoms of neuropathic pain are present in approximately 5% of the Western population and are a large burden to patients and their environment. On top of symptoms of neuropathic pain, the majority of patients also experience other symptoms such as alterations in mood, anxiety, sleep disorder and neurocognitive impairment. Treatment remains challenging due to the lack of adequate efficacy of currently available treatment options. Opportunities for future improvement of treatment efficacy lie in the implementation of personalized medicine by improvement and utilization of sensitive diagnostic tools to provide pain therapies based on patient characteristics rather than on underlying disease. Increasing knowledge on causes and consequences of individual disease patterns, including psychological factors, is necessary to improve accurate individualized pain management.

The aims of the current Research Topic are to (1) provide state-of-the art insights and knowledge on signs and symptoms of neuropathic pain; (2) present (novel) diagnostics and analyses techniques that aid in the identification of neuropathic pain patients; and (3) give an overview of a possible patient classification system to identify patient subgroups and guide appropriate treatment regimens. Both human and animal studies are considered for publication.


Keywords: Neuropathic Pain, Quantitative Sensory Testing, Phenotyping, Subgroup Analyses, Diagnostics


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

27 October 2020 Abstract
27 February 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

27 October 2020 Abstract
27 February 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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