Research Topic

Nucleic Acid Probe-Based Fluorescent Sensing and Imaging

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About this Research Topic

Nucleic acids are the biological carriers for genetic information. Mainly due to their great capacity for recognition, nucleic acids have been intensely exploited in developing probes such as molecular beacons, aptamers, and DNAzymes. There are advantages of multiple aspects to nucleic acid probes, including ...

Nucleic acids are the biological carriers for genetic information. Mainly due to their great capacity for recognition, nucleic acids have been intensely exploited in developing probes such as molecular beacons, aptamers, and DNAzymes. There are advantages of multiple aspects to nucleic acid probes, including programmability, diversity, artificial synthesis, cheapness, and easy modification. In particular, through integration with organic fluorogens or nanomaterials, fluorescent nucleic acid probes display great potential applications in biochemical sensing and cell imaging, by virtue of rapidity, sensitivity, high resolution, and visualization of fluorescence technology.

This Research Topic has been put forth in the service of improving the development of nucleic acid probes, as well as ushering in new breakthroughs in this fertile research area.

We welcome submissions of Original Research articles, Reviews, and Perspectives. Suggested themes for individual contributions may include (but are not limited to):

 • Fluorescent detection
 • Signal amplification technologies
 • Amplified detection
 • Amplified imaging of intracellular biomarkers
 • Nucleic acid probe-mediated therapy


Keywords: nucleic acid, probe, fluorescence, sensing, imaging, detection


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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