About this Research Topic
Nanobiotechnology is a special fusion of bio and nanotechnology that uses the idea of utilizing novel scientific approaches for manipulating genetic, molecular, and cellular processes to develop products at the nanoscale. This knowledge can be utilized for the synthesis of nano-products that can be applied in several avenues of the life sciences. The manipulation in structure, function, and properties of bioactive molecules with the help of advanced nanobiotechnology approaches is of great interest. An example is nanoparticle-based approaches which have led to nanoparticle embedded enzymes being used for the derivation or greener synthesis of the nutraceuticals compounds. Similarly, synthesis of artificial cells, tissue, or organs for implantations, synthesis of the supramolecular peptide, oligonucleotide nanocomplexes, DNA, and protein conjugates have also now become possible through bioengineering.
The newly developing technologies involving biomolecules modification/manipulation utilizing nanobiotechnological approaches can be applied in developing greener approaches for the production of biomedically important biomaterials. Still, there is a need to have a better understanding and derive technologies for the fabrication and synthesis of nanoengineered biomolecules, cells, and even organs. These strategies must focus on developing a simplistic yet accurate synthesis mechanism, have high structural integrity and functional control. Looking into the fast-growing field there is great scope for designing or synthesizing novel biomaterial with tailored functions for biomedical applications. Thus, to explore its full potential for better and enhanced applications rigorous study is still required.
Therefore, this Research Topic aims to collect recent pioneering and exceptional research works in the overlapping field of nanotechnology and biomolecular bioengineering with its application for the derivation of the biomaterials. It will provide an exceptional overview of all facets related to recent advances in the development of novel biomolecules utilizing nanobiotechnological approaches for the development of nano-biomolecules and nano-biosystems. The engineered biomolecules and biosystems can be further used for developing greener approaches for the derivation of biomedically important biomaterials. Hence, the themed collection will provide a platform to the researchers, pharmacists, and medical professionals to publish and showcase their latest findings and exciting results to the world related to green synthesis and applications of biomaterials derived with a fusion of nano-biotechnological and biomolecule bioengineering.
We welcome Original Research papers and Reviews/ Mini-Reviews on, but not limited to, the following topics:
• Synthesis of engineered nano-biomolecules such as proteins, enzymes, lipids, polysaccharides, nucleotides, etc.
• Application of advanced engineered nano-biomaterials in catalysis for synthesis of essential biomaterials
• Nano-biotechnological approaches in biomolecule bioengineering for the synthesis of:
- linkers and substrates for applications in diagnostic, biomaterial productions, controlled release of drugs
- artificial cells and organs, supramolecular peptides and oligonucleotide nano-complexes
- DNA conjugates with lipid, protein, enzymes, etc for application in diagnostics, and drug release at a specific target, life evolution, etc.
- fluorescence tagged biomaterials and DNA conjugated with lipids, proteins, etc. for application in bioimaging and diagnostics
Keywords: nano-biotechnology, biomolecules, bioengineering, Green synthesis, Biomedical
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.