About this Research Topic
Natural environments are recognized as reservoirs of antibiotics and antibiotic resistance genes. It has also been recognized that these environments may be relevant to the emergence and dissemination of antibiotic resistance due to the horizontal transfer of antibiotic resistance genes, which are located in mobile genetic elements and can move between pathogenic and environmental bacteria. However, research on antibiotic resistance has been mostly focused on clinical perspective, and the environmental aspect of it is characterised to a lesser extent.
Increased attention is directed towards the water resistome such as the emergence and spread of antibiotic resistance in aquatic environments. Occurrence and diversity of antimicrobial resistance genes in indigenous aquatic bacteria is a crucial research issue in the field of antibiotic resistance. Cyanobacteria are an essential component of the water microbiota and yet have to be thoroughly investigated concerning their role on environmental resistome.
Cyanobacteria in water are exposed to the environmental antimicrobial pollution and they also can be in close contact with other, often resistant, bacteria. Despite the important ecological role played by cyanobacteria in water environments, the studies on their role in water antimicrobial resistome have been initiated only very recently. The limited data available suggest that cyanobacteria may possess intrinsic and/or acquired resistance to some antimicrobials. However, this is just the beginning of a research area that needs to be developed further.
This Research Topic welcomes contributions focused on, but not limited exclusively, the characterization of antimicrobial susceptibility phenotypes and genotypes in cyanobacteria.
This article collection aims to gather a set of data that allow us to better understand the role of cyanobacteria in the environmental resistome and, in particular, to answer the following questions:
• Do cyanobacteria have reduced susceptibility to some antimicrobials?
• Do cyanobacteria exhibit a natural resistance to antimicrobials?
• Can cyanobacteria acquire/transfer antibiotic resistance genes from/to their bacterial neighbours?
• If there is a correlation between the antibiotic pressure in aquatic systems and antibiotic resistance in cyanobacteria?
• How can cyanobacteria adapt to antibiotic pollution and overcome the deleterious effects of antimicrobial residues?
• Are there any specific mechanisms determining reduced antibiotic susceptibility in cyanobacteria?
• If toxicity/bioactivity if cyanobacteria are related to their antimicrobial resistance?
Keywords: Cyanobacteria, Resistome, Antibiotics, Susceptibility, Toxicity/Bioactivity
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.