Research Topic

Advances in Opioid Analgesia and Addiction

About this Research Topic

Opioid abuse and the potential for overdose significantly limits the utility of this class of analgesics. As a consequence, a substantial number of chronic pain patients may be living with unrelieved pain due to inadequate pain management. Therefore, advances are needed to provide pain relief for moderate-to-severe chronic pain. A better understanding of the mechanisms of opioid analgesia and addiction, adjunct treatments for use with opioids, and novel treatments for opioid abuse are critically needed. Clinical studies of novel treatments, as well as preclinical investigations related to opioid analgesia and abuse will be considered. Manuscripts can take the form of original research, topical reviews or expert commentary.


Keywords: Opioids, Adjunct, Analgesia, Addiction, Abuse


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Opioid abuse and the potential for overdose significantly limits the utility of this class of analgesics. As a consequence, a substantial number of chronic pain patients may be living with unrelieved pain due to inadequate pain management. Therefore, advances are needed to provide pain relief for moderate-to-severe chronic pain. A better understanding of the mechanisms of opioid analgesia and addiction, adjunct treatments for use with opioids, and novel treatments for opioid abuse are critically needed. Clinical studies of novel treatments, as well as preclinical investigations related to opioid analgesia and abuse will be considered. Manuscripts can take the form of original research, topical reviews or expert commentary.


Keywords: Opioids, Adjunct, Analgesia, Addiction, Abuse


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

27 October 2020 Abstract
27 February 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

27 October 2020 Abstract
27 February 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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