About this Research Topic
Opioid abuse and the potential for overdose significantly limits the utility of this class of analgesics. As a consequence, a substantial number of chronic pain patients may be living with unrelieved pain due to inadequate pain management. Therefore, advances are needed to provide pain relief for moderate-to-severe chronic pain. A better understanding of the mechanisms of opioid analgesia and addiction, adjunct treatments for use with opioids, and novel treatments for opioid abuse are critically needed. Clinical studies of novel treatments, as well as preclinical investigations related to opioid analgesia and abuse will be considered. Manuscripts can take the form of original research, topical reviews or expert commentary.
Keywords: Opioids, Adjunct, Analgesia, Addiction, Abuse
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