About this Research Topic
The asthma treatment guidelines have seen several new treatment options added in the past years, particularly for severe asthma- in which T2 biologicals form an important new class of add-on therapeutics. Despite these recent additions, only a sub-population of severe asthmatics are responsive to these new biologics and an unmet clinical need remains- particularly as it pertains to inflammation and re-modelling in severe asthma.
This collection will address potential new mechanisms and therapeutic targets for asthma in an explorative fashion, with the aim of paving the way for a new generation of pharmacological or non-pharmacological treatments. This will be achieved by highlighting mechanisms of inflammation and remodeling in asthma, and by reviewing key ongoing developments in asthma pharmacology.
Keywords: inflammation, asthma, remodeling, pharmacology, pathophysiology
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