Research Topic

Environmental insults during and beyond pregnancy: a life-course perspective

About this Research Topic

Today, people are increasingly exposed to a diverse range of environmental insults including air pollution, climate change, wildfires, pesticides, and other chemicals found in the environment as well as common consumer products. Studies consistently show that these environmental hazards are associated with increased short- and long-term risk of a wide range of health outcomes across the lifespan. Growing evidence also suggests that there are critical periods of growth and development during the life course when environmental exposures do more damage to health than they would at other times. This may mean that environmental insults encountered during early life may have life-long effects, and the cumulative and interactive effects of these exposures may occur not only across an individual’s life but also across generations.

It is critical to understand the independent and combined effects of common environmental insults on health across and beyond an individual’s lifespan. Such knowledge can help identify chains of risk that can be broken and times of intervention that may be effective to promote health across the lifespan. With this Research Topic, we aim to provide an updated overview of clinical and epidemiological studies investigating health effects of various environmental insults across the lifespan.

We welcome Original Research investigations and Review Articles on, but not limited to, the following scope:
• Exposure and risk assessments of environmental insults across and beyond a person’s lifespan, with a focus on the physical environment
• Identification of critical windows of exposure
• Identification of susceptible populations
• Exploration of the complex interaction between exposures as well as the gene-environment interaction
• Intervention addressing environmental insults across the life span
• Methodological advancement


Keywords: Environmental exposures, Pollution, Early life, Prenatal exposures, Life-course, Development


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Today, people are increasingly exposed to a diverse range of environmental insults including air pollution, climate change, wildfires, pesticides, and other chemicals found in the environment as well as common consumer products. Studies consistently show that these environmental hazards are associated with increased short- and long-term risk of a wide range of health outcomes across the lifespan. Growing evidence also suggests that there are critical periods of growth and development during the life course when environmental exposures do more damage to health than they would at other times. This may mean that environmental insults encountered during early life may have life-long effects, and the cumulative and interactive effects of these exposures may occur not only across an individual’s life but also across generations.

It is critical to understand the independent and combined effects of common environmental insults on health across and beyond an individual’s lifespan. Such knowledge can help identify chains of risk that can be broken and times of intervention that may be effective to promote health across the lifespan. With this Research Topic, we aim to provide an updated overview of clinical and epidemiological studies investigating health effects of various environmental insults across the lifespan.

We welcome Original Research investigations and Review Articles on, but not limited to, the following scope:
• Exposure and risk assessments of environmental insults across and beyond a person’s lifespan, with a focus on the physical environment
• Identification of critical windows of exposure
• Identification of susceptible populations
• Exploration of the complex interaction between exposures as well as the gene-environment interaction
• Intervention addressing environmental insults across the life span
• Methodological advancement


Keywords: Environmental exposures, Pollution, Early life, Prenatal exposures, Life-course, Development


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

25 December 2020 Abstract
25 June 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

25 December 2020 Abstract
25 June 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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