About this Research Topic
Over the past two decades, zinc oxide nanoparticles (ZnO NPs) have shown promising results in the biomedical field thanks to their outstanding properties including biocompatibility, low-cost synthesis, and FDA approval under the topical segment. Due to these unique traits, Zinc oxide nanoparticles have demonstrated its footprint in the field of cancer therapy (therapy and diagnosis) and the Anti-microbial fields. Zinc is also well known for maintaining the structural integrity of insulin, so predicting the use of zinc oxide NPs for the successful treatment of diabetes is not going to be over-ambitious soon.
Since most properties of zinc oxide depend on the size, designing, and tailoring the device according to applicability is one of the biggest challenges. One of these size-based properties is the release of excess reactive oxygen species (ROS) and zinc ions to cause apoptosis in cancer cells or antimicrobial activity. More specifically, zinc oxide (ZnO) is one of the materials that can be used to utilize the beneficial effects of the nanoscale as it can develop into a remarkable variety of morphologies to tune according to biomedical applicability. There is an emerging need to develop a wider range of zinc oxide and zinc oxide morphologies (composites or core-shell) based structure by applying the core principles of nanotechnology for possible biomedical applications. Although a great deal of effort has been undertaken in this area, major challenges remain to be tackled.
This Research Topic aims at gathering together a collection of articles (Original Research and Reviews) focusing at both the translation as well as basic science aspects of ZnO and ZnO based nanomaterials. We are planning to develop a focused issue that will serve not only the current state-of-the-art in the field of Zinc oxide nanoparticles, but will further provide insightful aspects on ZnO-based hybrid tunable combinations with other nanomaterials over a broad discipline of biomedical applications that this material can achieve.
Topics include, but are not limited to:
• Synthesis of novel morphologies or hybrid synthesis of ZnO nanoparticles for efficient biomedical application
• Tuneable synthesis ZnO nanoparticles for targeted drug delivery applications
• Development of Zinc oxide based hybrid material for anti-biofilm applications
• Biomedical based applications of ZnO nanoparticles/ ZnO based nanomaterials
• Development of ZnO nanoparticles/ ZnO based nanomaterials as an anti-diabetic agent
• Application in cancer theranostics and bio imagining
• Molecular mechanistic approach of zinc oxide nanoparticles for biomedical application/s including antidiabetic phenomenon, anti-cancer activity, and antimicrobial activity
• Hybrid nanostructures of ZnO with enhanced properties
Keywords: Zinc Oxide, Zinc Oxide Nanomaterials, Biomedical Applications, ZnO, drug delivery, cancer theranostics, bio-imaging, anti-diabetic, nanostructures
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.