About this Research Topic
Neuron-glial interaction is considered a critical mechanism involved in the enhancement of TG neuronal excitability. It is also known that macrophages accumulate in the TG following trigeminal nerve injury. Macrophage accumulation occurs in the TG after trigeminal nerve injury. Activated glial cells and macrophages generate and release various molecules, and neuron-glial cell and neuron-macrophage communication occurs. This communication spreads in a wide area of the sensory ganglion, and injured and uninjured primary neurons are further activated, contributing to persistent pain occurrence. The section aims at publishing important basic research, as well as translational and clinical findings in the field of neuron-glial interaction . The scope of the specialty section is broad, covering all scientific topics and techniques of relevance to the field, from molecular and cellular aspects to animal models and humans. Our goal is to provide a comprehensive forum through which quality research can be disseminated to a wide audience.
Keywords: Pain, Sensory Ganglion, Satellite Cell, Macrophage, Primary Neuron
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