Research Topic

Drug discovery at G protein-coupled receptors for metabolic intermediates

  • Submission closed.

About this Research Topic

Over the past decade, G protein-coupled receptor deorphanization programmes have revealed an unlikely source of endogenous ligands - metabolic intermediates. Various metabolic intermediate/receptor pairs have since been implicated in several physiological and pathological processes, such as diabetes, lipid ...

Over the past decade, G protein-coupled receptor deorphanization programmes have revealed an unlikely source of endogenous ligands - metabolic intermediates. Various metabolic intermediate/receptor pairs have since been implicated in several physiological and pathological processes, such as diabetes, lipid handling and hypertension. In this Research Topic, the challenges of drug discovery at these often low potency and poorly defined receptors is explored with emphasis on Free Fatty Acid receptors 1, 2 and 3, GPR120, TGR5, GPR81, GPR35, SUCNR1 and GPR109A and GPR109B.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Recent Articles

Loading..

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..

Topic Editors

Loading..

Submission Deadlines

Submission closed.

Participating Journals

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top