Research Topic

Hydrogels for Wound Management: Biosynthesis, Design and Applications

About this Research Topic

Superabsorbent materials (hydrogels) are three-dimensional hydrophilic networks able to absorb large quantities of water or liquids. Since the commercialization of the first superabsorbent materials in 1978, the global use of hydrogels has dramatically increased and keeps on expanding year by year. Hydrogel applications now range from health care products, biomedicine, biosensors, pharmaceutical materials, tissue engineering platforms, food industry, environmental applications, separation materials, fibers/textiles, water-swelling rubbers, biomedical applications, electroactive materials, construction and sealing materials, etc.. Due to the growing need/ use of superabsorbent materials, several new physical, chemical, and biobased techniques and designs are being developed.

This special issue will focus on providing state of the art of advances in biotechnology and bioengineering in the synthesis, design and application of hydrogels for wound management. Critical in this special issue is also to highlight the design of the hydrogels as materials that actively participate in promoting the wound healing process. Further, each part of this issue will provide a concise overview of the successes, challenges and a look into the future trends in this exciting field.

Despite impressive advances in the development of hydrogels for wound management and increasing acceptance in the healthcare industry, there is hardly any dedicated activity summarizing these advances for the benefit of the reader, scientists and health care specialists. The major goal of this Research Topic is to provide state of the art advances in biotechnology and bioengineering in the development (synthesis, design and application) of hydrogels as active materials for wound management. Thus the Research Topic will focus on the major strategies used for the synthesis of hydrogels, focusing on the key choices to be made in terms of the chemical and structural properties of the backbone polymer, the nature of the crosslinking strategy used (in terms of both the mechanism and the permanence of network formation), and how these hydrogels assist/promote the wound healing process. The impacts of these various choices on the ultimate properties of the hydrogels generated will be emphasized in the context of the rational design of hydrogel compositions, structures for target applications, impact on the wound healing process and future trends.

Original Research, as well as Reviews, focusing on the following sub-themes are encouraged:
• Synthesis of bioactive wound dressings
• Wound dressing engineered 3-D scaffolds
• Wound dressing tissue engineered platform
• Wound dressing designed for chronic wounds
• Bioengineered skin substitutes
• Dressings with integrated sensors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Superabsorbent materials (hydrogels) are three-dimensional hydrophilic networks able to absorb large quantities of water or liquids. Since the commercialization of the first superabsorbent materials in 1978, the global use of hydrogels has dramatically increased and keeps on expanding year by year. Hydrogel applications now range from health care products, biomedicine, biosensors, pharmaceutical materials, tissue engineering platforms, food industry, environmental applications, separation materials, fibers/textiles, water-swelling rubbers, biomedical applications, electroactive materials, construction and sealing materials, etc.. Due to the growing need/ use of superabsorbent materials, several new physical, chemical, and biobased techniques and designs are being developed.

This special issue will focus on providing state of the art of advances in biotechnology and bioengineering in the synthesis, design and application of hydrogels for wound management. Critical in this special issue is also to highlight the design of the hydrogels as materials that actively participate in promoting the wound healing process. Further, each part of this issue will provide a concise overview of the successes, challenges and a look into the future trends in this exciting field.

Despite impressive advances in the development of hydrogels for wound management and increasing acceptance in the healthcare industry, there is hardly any dedicated activity summarizing these advances for the benefit of the reader, scientists and health care specialists. The major goal of this Research Topic is to provide state of the art advances in biotechnology and bioengineering in the development (synthesis, design and application) of hydrogels as active materials for wound management. Thus the Research Topic will focus on the major strategies used for the synthesis of hydrogels, focusing on the key choices to be made in terms of the chemical and structural properties of the backbone polymer, the nature of the crosslinking strategy used (in terms of both the mechanism and the permanence of network formation), and how these hydrogels assist/promote the wound healing process. The impacts of these various choices on the ultimate properties of the hydrogels generated will be emphasized in the context of the rational design of hydrogel compositions, structures for target applications, impact on the wound healing process and future trends.

Original Research, as well as Reviews, focusing on the following sub-themes are encouraged:
• Synthesis of bioactive wound dressings
• Wound dressing engineered 3-D scaffolds
• Wound dressing tissue engineered platform
• Wound dressing designed for chronic wounds
• Bioengineered skin substitutes
• Dressings with integrated sensors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

02 November 2020 Abstract
02 March 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

02 November 2020 Abstract
02 March 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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