About this Research Topic
For sure within the life span of red blood cells many cellular properties change leading to aged mixed cell populations in the circulation. Although red blood cells seem to be genetically terminated by the time they become red blood cells there are surprisingly versatile remodeling processes happening during their life span. Numerous disorders are believed to be associated with the aging process of red blood cells. Furthermore, in vitro aging and/or modifications as well as the slowing down of the modifications is an important issue in transfusion medicine.
However, many of the mechanisms behind such effects are far from being fully understood. In this context the Research Topic is set to include articles in the field of biochemical investigations, biophysical approaches, physiological and clinical studies related to red blood cell maturation and aging. This includes Original Research, Methods, Hypothesis and Theory, Reviews and Perspectives.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.