About this Research Topic
Infectious diseases remain a global threat with a significant detrimental impact on health, economies and security. Infectious disease research has benefited from unprecedented advances in microbial genomic data collection, analyses and storage. Indeed, whole-genome information is now commonly applied in clinical disease diagnoses, management and public health surveillance. Deep mining of large-scale historical and contemporaneous data sets has led to an understanding of how infectious diseases spread over geographic and temporal scales, within the environment and in different host populations. Microorganisms do not exist in a vacuum. The global challenges of health security, socioeconomic inequity and climate change mandates a multi-disciplinary and collaborative approach to further understand how infectious diseases emerge as well as in the development of control measures.
While we capture or predictively model the microbe-specific factors that underlie transmission, the results from these endeavors are often not interpreted within the context of the intricate set of factors that drive the emergence of infectious diseases. The convergence of these complex factors leads to harsher and intractable consequences. This Research Topic will explore this intersection with the aim of revealing a new cache of information to highlight new areas of research that can assist all stakeholders (researchers, clinicians, policymakers and the concerned public) in developing sustainable and equitable solutions for infectious diseases control.
Areas to be covered in this Research Topic include, but are not limited to, the following:
• Environmental perturbation that impacts natural microbial reservoirs and hosts leading to emergence and re-emergence of microbial pathotypes.
• Microbial genomic variation which has led to the emergence of pathogenic lineages with altered (greater) transmissibility, infectivity, adaptability and pathogenicity.
• Current and historical socio-economic and political factors that underscore infectious diseases management and policies: successes and failures
• Exploration of the intersectionality of all three above to develop and implement best-fit and equitable solutions to current and future public health threats.
• Original Research articles, Reviews, Communications, Perspectives on any of the themes listed above will be considered.
Keywords: Microbial communities, Genomic variation, Public Health determinants, Infectious diseases, Epidemiology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.