Research Topic

The Power of Interactions in Regenerative Medicine and Dentistry

About this Research Topic

The field of tissue regeneration is a booming field, not only of research, but also of clinical translation. In the past, it was thought to only have mainly three pillars: stem cells, scaffolds, and growth factors. However, as the field progressed, many interactions that determine and influence tissue regeneration strategies have been discovered, making the characterization of interfaces and interactions between biomaterials (scaffolds), cells, extracellular matrix, microbes, drugs, mechanical loading, electric and ultrasonic stimuli, of eminent importance.

The aim of this Research Topic is to investigate a plethora of interactions in tissue regeneration, which will determine the future of regenerative strategies and their clinical translation into medical and dental therapies.

Topics of interest include, but are not limited to:
• The interface between biomaterials and tissues
• Biomaterials as scaffolds in tissue regeneration including cell-materials interactions
• Biomaterials with antimicrobial activity (the interaction with the microbiome)
• Cells -Extracellular matrix interactions including stem cells characterization, signaling pathways, growth factors, and biomineralization in regenerative medicine and dentistry
• The role of ultrasound and electric stimulation in tissue regeneration including piezoelectric smart biomaterials


Keywords: regeneration, biomaterials, interactions, antimicrobial, growth factors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The field of tissue regeneration is a booming field, not only of research, but also of clinical translation. In the past, it was thought to only have mainly three pillars: stem cells, scaffolds, and growth factors. However, as the field progressed, many interactions that determine and influence tissue regeneration strategies have been discovered, making the characterization of interfaces and interactions between biomaterials (scaffolds), cells, extracellular matrix, microbes, drugs, mechanical loading, electric and ultrasonic stimuli, of eminent importance.

The aim of this Research Topic is to investigate a plethora of interactions in tissue regeneration, which will determine the future of regenerative strategies and their clinical translation into medical and dental therapies.

Topics of interest include, but are not limited to:
• The interface between biomaterials and tissues
• Biomaterials as scaffolds in tissue regeneration including cell-materials interactions
• Biomaterials with antimicrobial activity (the interaction with the microbiome)
• Cells -Extracellular matrix interactions including stem cells characterization, signaling pathways, growth factors, and biomineralization in regenerative medicine and dentistry
• The role of ultrasound and electric stimulation in tissue regeneration including piezoelectric smart biomaterials


Keywords: regeneration, biomaterials, interactions, antimicrobial, growth factors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Topic Editors

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Submission Deadlines

29 March 2021 Manuscript
30 June 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

29 March 2021 Manuscript
30 June 2021 Manuscript Extension

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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