About this Research Topic
Phthalocyanines have been recognized as biomimetic complexes as well as a pivotal class of compounds with a substantial number of cutting-edge applications. Metallophthalocyanines and their derivatives are extensively deployed as dyes, optical materials, solar cells, photosensitizer agents, fluorescence “off-on-off” sensors, and electrical devices, as well as catalysts in chemical processes and organic transformations. The most important feature that renders these molecules promising candidates in the domain of materials is their versatility and chemical and thermal stability. Two hydrogen atoms of the central cavity in metal-free phthalocyanines can be replaced by more than 70 central metals, and assorted substituents can be incorporated. Furthermore, they can be functionalized with almost every organic/inorganic functional group via diverse organic reactions, thus further extending the attractive properties of these molecules. Owing to their macrocyclic nature with extended π-systems, phthalocyanines are capable of undergoing fast redox processes such as oxidation of organic compounds, epoxidation, oxygen reduction reactions, CO2 reduction, and hydrogen evolution reactions, important both in academia and in industry.
The aim of this Research Topic is to become the point of reference with regard to recent trends in phthalocyanine research. Although the low solubility of methallophthalocyanines in water or polar solvents and their high aggregation tendency hampers their application in medicinal fields, by rationally tuning the metal center, as well as the functionalization of substrates, important characteristics of these molecules such as electrical and optical properties, intermolecular interactions, solubility, and dispersity could be fine-tuned. This modification can play crucial roles in the plethora of biomedical applications, for instance photodynamic therapy as a clinically approved method for cancer treatment. Apart from the diverse application of phthalocyanines, in past decades, the synthesis of these interesting macrocycles has posed some major challenges. As a consequence, scientists have introduced novel initiatives to effectively access these valuable compounds. Even so, there is still room for improvement of these synthetic routes by taking sustainable and green chemistry principles into account.
We welcome Original Research, Review, Mini Review, and Perspective articles, in themes including but not limited to:
• Design and synthesis of novel phthalocyanines
• Green and sustainable synthetic pathways of phthalocyanines
• Preparation of phthalocyanine hybrid composites
• Computational methods and computer modelling of phthalocyanines
• Studies on the optical and electrical properties of phthalocyanines
• Applications of novel phthalocyanines in diverse fields (photocatalysts, biomedical, biosensors and chemosensors, photodynamic therapy, solar cells etc.)
Keywords: Phthalocyanines, Biomimetic complexes, Photosensitive agents, Catalysis, Biomedical applications
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.