About this Research Topic
This Research Topic will examine progress in understanding cortical wiring principles. This Research Topic aims to draw together recent advances in methods and understanding as well as recent challenges to existing ideas about how cerebral cortex is wired. This is particularly timely because new automated techniques may soon yield huge datasets in need of explanation. Recent studies have, for instance, empirically evaluated Rámon y Cajal's conservation laws for cerebral cortex, while others have shown some unexpected connectivity features that may refine the traditional view of how corticocortical connections are organised with regard to functional representations of auditory, somatosensory and visual cortices. Understanding these data will help improve the fidelity of neural models of cerebral cortical function and take into account the diversity of connections at both micro- and mesoscopic scales not seen at such a depth before.
We particularly welcome contributions based on experimental findings. To help readers gain a fuller appreciation of the topic, contributions ought to include a review-style introduction to the current state of the field and ideally deal with conceptual considerations of cortical wiring. Below we provide example topics of interest for potential contributors though we are happy to discuss whether specific proposals fit within the scope of the Research Topic.
Example topics of interest are:
- Structure-function relationships in association, sensory, or motor cortex.
- Species differences or invariances in cortical wiring principles.
- Novel techniques used to reveal wiring principles.
- Fine-scale cortical wiring rules.
- Resource limitations and constraints on cortical wiring design.
- Scaling and cortical wiring principles.
- Developmental and reorganizational cortical wiring principles.
- Pathological approaches to understanding cortical wiring principles.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.