About this Research Topic
Many serious liver diseases affecting millions of people worldwide cannot be treated despite concerted efforts. This warrants a search for new therapeutic strategies. Recent advances in the biomedical application of novel nanomaterials aim towards the controllable drug delivery for targeting, diagnosis and therapy in liver diseases, including non-alcoholic fatty liver disease, diabetes, obesity etc. The rational design and engineering of functionalized nanoparticles, including inorganic nanomaterials, polymers, liposomes, and peptide nanomaterials, have gained momentum in novel pathophysiology-oriented therapy for liver disease. Therefore, the development of such novel multifunctional platforms for the delivery of small drug molecules, proteins, and nucleic acids to the liver poses a promising therapeutic route in the near future.
The goal of the Research Topic is to cover the latest advances in the design and synthesis of novel nanomaterials for liver disease, including targeted delivery, imaging, and therapy.
We welcome submissions of Original Research and Review articles in themes including, but not limited to:
• Synthesis and characterization of novel functionalized nanomaterials for liver disease
• Impact of synthesis parameters and physicochemical properties of nanomaterials on targeting liver disease
• Design and synthesis of advanced nanomaterials for the clinical diagnosis and therapy of liver disease
• Hepatic metabolism and elimination mechanism of nanoparticles
Keywords: Advanced nanomaterials, functionalized nanomaterials, novel nanomaterials, liver targeted nanomaterials, drug delivery, liver disease diagnosis and therapy
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.