About this Research Topic
The goal of this collection is to synthesize the research investigating the role of epigenetic processes in neuropsychiatric disorders, such as mood disorders, addiction, psychosis, autism spectrum disorders, and neurodegenerative diseases. Through a comprehensive profiling and assessment of both original studies and reviews on the topic, the editors aim to compile an important collection of articles which identify epigenetic modifiers associated with neuropsychiatric disorders. A special emphasis will be on epigenetic pathways that are offset by specific environmental exposures and/or life experiences and are crucial to the development, progression, and/or transmission of neuropsychiatric disorders.
The research topic welcomes studies broadly related to the following themes:
1. Basic science studies involving disease models, or clinical studies of patient populations, on the role of established epigenetic processes (histone modifications, DNA methylation/hydroxymethylation, and non-coding RNAs) in risk, pathogenesis, prognosis, or inheritance of neuropsychiatric disorders.
2. Basic science studies not involving disease models on the role of novel epigenetic processes (including chromatin looping, nucleosome organization, prions, epigenetic drift induced by DNA breaks, and RNA modification) in the regulation of neurocognitive and/or behavioral processes with postulated disease relevance.
3. Review articles on the involvement of specific epigenetic processes in neuropsychiatric disorders and/or neurocognitive perturbations with a translational focus.
Submission types include Original Research, Brief Research Report, Review, and Mini Review.
Keywords: epigenetics, neuropsychiatric disorders, risk, environment, brain
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.