Research Topic

Perinatal Endocrinology and Pregnancy-Related Endocrine Disorders

About this Research Topic

Endocrine disorders during pregnancy are a major concern due to their adverse impact on maternal and offspring health. Profound hormonal changes that occur during pregnancy play an important role in maternal physiological adaptation and endocrine homeostasis is important for a successful pregnancy and its favorable outcome. The role of hormones in maintaining normal metabolism and supporting physiological functions of the mother and fetus during pregnancy cannot be overemphasized.

Research in the field of perinatal endocrinology is growing exponentially both in basic science as well as in translational clinical medicine. Emerging technologies in molecular biology, use of mega-data, and artificial intelligence are some of the driving factors. Significant progress has been made in recent years in our understanding of key regulatory mechanisms involved in the pathophysiology of pregnancy-related endocrine disorders, associated risk factors, and their short- and long-term consequences. Findings of such research are important and need to be effectively communicated.

This Research Topic aims to disseminate current best evidence in the field of perinatal endocrinology with a focus on pregnancy-associated endocrine disorders. It will also cover the issues related to clinical practice of screening, diagnosis, and management of common endocrine disorders during the preconception period, pregnancy and postpartum.

This Research Topic welcomes submissions of Reviews, Original Research, and Systematic Reviews related to the following areas:
• Physiological endocrine changes in pregnancy;
• Regulatory factors, underlying mechanisms, and pathophysiological characteristics of pregnancy-associated endocrine disorders and their management;
• Endocrine regulation of lactation and lactation failure;
• Role of intrinsic and exogenic factors including genetic predisposition, phenotype, lifestyle, and environmental factors including endocrine disruptors in the risk modification and etiology of pregnancy-related endocrine disorders;
• New concepts in the pathogenesis and regulatory mechanism of thyroid disease in pregnancy and the postpartum period;
• Studies on pregnancy-related metabolic disorders including gestational diabetes and their impact on pregnancy outcome;
Studies on endocrine regulation of eating disorders during pregnancy and their management;
• Placental endocrine physiology and pregnancy related conditions associated with placental endocrine dysfunction;
Placental hormones as the biomarkers of pregnancy complications and long-term health;
• Role of hormones in conception/fertilization, in vitro embryonic development, implantation and in the management of implantation failure and miscarriage.


Keywords: Perinatal endocrinology, Pregnancy, Placenta, Gestational Diabetes, Placental peptides, Placental hormones, Maternal endocrine physiology


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Endocrine disorders during pregnancy are a major concern due to their adverse impact on maternal and offspring health. Profound hormonal changes that occur during pregnancy play an important role in maternal physiological adaptation and endocrine homeostasis is important for a successful pregnancy and its favorable outcome. The role of hormones in maintaining normal metabolism and supporting physiological functions of the mother and fetus during pregnancy cannot be overemphasized.

Research in the field of perinatal endocrinology is growing exponentially both in basic science as well as in translational clinical medicine. Emerging technologies in molecular biology, use of mega-data, and artificial intelligence are some of the driving factors. Significant progress has been made in recent years in our understanding of key regulatory mechanisms involved in the pathophysiology of pregnancy-related endocrine disorders, associated risk factors, and their short- and long-term consequences. Findings of such research are important and need to be effectively communicated.

This Research Topic aims to disseminate current best evidence in the field of perinatal endocrinology with a focus on pregnancy-associated endocrine disorders. It will also cover the issues related to clinical practice of screening, diagnosis, and management of common endocrine disorders during the preconception period, pregnancy and postpartum.

This Research Topic welcomes submissions of Reviews, Original Research, and Systematic Reviews related to the following areas:
• Physiological endocrine changes in pregnancy;
• Regulatory factors, underlying mechanisms, and pathophysiological characteristics of pregnancy-associated endocrine disorders and their management;
• Endocrine regulation of lactation and lactation failure;
• Role of intrinsic and exogenic factors including genetic predisposition, phenotype, lifestyle, and environmental factors including endocrine disruptors in the risk modification and etiology of pregnancy-related endocrine disorders;
• New concepts in the pathogenesis and regulatory mechanism of thyroid disease in pregnancy and the postpartum period;
• Studies on pregnancy-related metabolic disorders including gestational diabetes and their impact on pregnancy outcome;
Studies on endocrine regulation of eating disorders during pregnancy and their management;
• Placental endocrine physiology and pregnancy related conditions associated with placental endocrine dysfunction;
Placental hormones as the biomarkers of pregnancy complications and long-term health;
• Role of hormones in conception/fertilization, in vitro embryonic development, implantation and in the management of implantation failure and miscarriage.


Keywords: Perinatal endocrinology, Pregnancy, Placenta, Gestational Diabetes, Placental peptides, Placental hormones, Maternal endocrine physiology


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

08 March 2021 Abstract
23 June 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

08 March 2021 Abstract
23 June 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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