About this Research Topic
Light microscopy is a cornerstone of the biological sciences. Over the past few centuries, innovation in technologies and education have driven discovery in cell and developmental biology, including the development of many advances for live cell imaging. With innovation comes new challenges in training, education, engineering and biological applications. Light microscopists working in the area of cell and developmental biology have developed innovative and effective new techniques, policies, protocols and tools to catalyze research progress with live cell microscopy.
Our goal is to provide a comprehensive resource for cell and developmental biologists interested in utilizing live cell microscopy methods to investigate molecular and cellular dynamics and organization. Many recent developments made by researchers, Core facility staff, vendors, and the global microscopy and cell and developmental biology communities have led to unprecedented access to monitor the dynamics and organization within living cells. Live cell microscopy methods have been adapted to enable investigations ranging from the movement of single molecules to multiple days, required for investigation of developmental processes. For many of these techniques, local expertise may not be available, and it is therefore critical to adapt to more remote/virtual research/teaching realities, which will allow researchers to make a judicious choice about imaging techniques suited for specific biological applications. Establishing best practices and sharing recent developments is essential to continue to support the growing microscopy needs in the cell and developmental community.
The aim of the current Research Topic is to cover promising, recent, and novel research trends in the use of light microscopy applied to cell and developmental biology during the COVID pandemic. Areas to be covered in this Research Topic may include, but are not limited to:
● What new developments have been made to enable state-of-the-art live cell microscopy methods?
● How can live cell microscopy methods be applied to uncover novel dynamics and organization in living cells?
● What specific considerations and developments have been made regarding hardware and technology for acquisition, sample preparation and sample mounting to enable enhanced spatial or temporal resolution with live cell microscopy?
● What are some of the best practices regarding analysis and processing of live cell microscopy data?
● What infrastructure is needed to develop and disseminate novel live cell technologies?
● Leveraging image analysis infrastructure and resources remotely
● What are best practices regarding teaching and training cell and developmental biologists new techniques in live cell microscopy?
● What are the fundamentals that cell and developmental biologists should understand about these methodologies?
● How do you provide effective virtual/remote training for these methods?
Topic Editor Paul Maddox is co-founder of Mizar Imaging
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.