Research Topic

Micro/Nano Manipulation Tools for Biological Characterization, In Vivo Navigation, and Drug Delivery

About this Research Topic

From optical tweezers to robotic actuation field generation systems, the development of micromanipulation systems, driven by optical, magnetic, acoustic, fluidic, and electric fields, has enabled a multitude of applications for mechanical characterization, in vivo navigation, and drug delivery. Across the scales, from tens of nanometers to hundreds of micrometers, the studies on micromanipulation tools address challenges on propulsion, friction, and fluidic drag, imposed by the small scale of the object. Recent studies on the actuation, locomotion and control enabled micromanipulation tools may act as platform technologies for addressing biological questions, minimally invasive surgery, and target drug delivery. This Research Topic highlights the interdisciplinary nature of micromanipulation studies, addressing long-lasting challenges both technically and scientifically.

Using micro/nano end-effectors as manipulation tools encounters several critical challenges, for example, actuation in low-Reynolds number fluid, precise force control, efficient navigation and control, and materials and structure design for drug delivery. This Research Topic intends to take the state-of-art of these research fields, from material design, actuation and control strategy, to biomedical applications. This Research Topic is established as an open platform for collecting papers that will attract broad interest from researchers in relative areas. We aim for the collection to present the recent advances of micro/nanomanipulators aimed towards biological characterization, in-vivo navigation and drug delivery.

The innovative designs of micro/nanomanipulation tools cover an extremely wide range of emerging biomedical applications. In this Research Topic, we strongly encourage researchers to submit works related to the design, fabrication, actuation, locomotion, and control of micro/nanomanipulation tools as well as the biomedical applications of these tools such as biological characterization, in vivo navigation and drug delivery. Potential topics include, but are not limited to:

• Biomedical micro/nanomanipulation tool design and development
• Actuation mechanisms for micro/nanomanipulation tools in biomedical environments
• Locomotion mechanisms for micro/nanomanipulation tools in biomedical environments
• Control theories for micro/nanomanipulation tools
• Micro/nanomanipulation tools for biological characterization
• Micro/nanomanipulation tools for in vivo navigation
• Micro/nanomanipulation tools for drug delivery


Keywords: micro/nano robotics, biomedical robotics, biophysics, locomotion, drug delivery


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

From optical tweezers to robotic actuation field generation systems, the development of micromanipulation systems, driven by optical, magnetic, acoustic, fluidic, and electric fields, has enabled a multitude of applications for mechanical characterization, in vivo navigation, and drug delivery. Across the scales, from tens of nanometers to hundreds of micrometers, the studies on micromanipulation tools address challenges on propulsion, friction, and fluidic drag, imposed by the small scale of the object. Recent studies on the actuation, locomotion and control enabled micromanipulation tools may act as platform technologies for addressing biological questions, minimally invasive surgery, and target drug delivery. This Research Topic highlights the interdisciplinary nature of micromanipulation studies, addressing long-lasting challenges both technically and scientifically.

Using micro/nano end-effectors as manipulation tools encounters several critical challenges, for example, actuation in low-Reynolds number fluid, precise force control, efficient navigation and control, and materials and structure design for drug delivery. This Research Topic intends to take the state-of-art of these research fields, from material design, actuation and control strategy, to biomedical applications. This Research Topic is established as an open platform for collecting papers that will attract broad interest from researchers in relative areas. We aim for the collection to present the recent advances of micro/nanomanipulators aimed towards biological characterization, in-vivo navigation and drug delivery.

The innovative designs of micro/nanomanipulation tools cover an extremely wide range of emerging biomedical applications. In this Research Topic, we strongly encourage researchers to submit works related to the design, fabrication, actuation, locomotion, and control of micro/nanomanipulation tools as well as the biomedical applications of these tools such as biological characterization, in vivo navigation and drug delivery. Potential topics include, but are not limited to:

• Biomedical micro/nanomanipulation tool design and development
• Actuation mechanisms for micro/nanomanipulation tools in biomedical environments
• Locomotion mechanisms for micro/nanomanipulation tools in biomedical environments
• Control theories for micro/nanomanipulation tools
• Micro/nanomanipulation tools for biological characterization
• Micro/nanomanipulation tools for in vivo navigation
• Micro/nanomanipulation tools for drug delivery


Keywords: micro/nano robotics, biomedical robotics, biophysics, locomotion, drug delivery


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

17 January 2021 Abstract
11 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

17 January 2021 Abstract
11 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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