About this Research Topic
Genetics are estimated to play an important part in endocrine and metabolic diseases. Genetic variants my in rare cases be disease causing or in more frequent cases be a risk factor for diseases. It is believed that in many cases it is the combination of several risk variants that define the susceptibility of a person to develop a specific disease. Recent sequencing studies in thousands of humans, either composed of control groups or different disease groups, provide now an access to a rich source of information that help to establish risk variants. Risk variants can be either frequent or rare. Precise knowledge about the underlying mechanisms will help in the future to propose either tailored medication or gene therapy.
During the « International Conference on Innovative Solutions: Cancer, Aging and Genetic diseases » held as Worldwide Live Remote Conference from October 27 to 30, 2020, more the 200 experts, especially from China, Kazakhstan and France - Academic, Medical, Investors and Industrial players- will discuss about the latest trends in the field of genetic diseases.
This special issue of Frontiers in Endocrinology welcomes submissions (original articles, comments, reviews) of all participating labs of this International Congress that are of relevance to endocrinology in relation to genetic diseases. Contribution from other labs are also welcome.
Potential contributions are invited in, but not limited to, the following fields:
· Functional consequences of risk variants on protein expression, structure, functional properties etc.
· Cellular consequences of risk variants
· Animal models of genetic endocrine and metabolic diseases
· Clinical aspects of genetic endocrine and metabolic diseases
· Epidemiological aspects in genetic endocrine and metabolic diseases
Keywords: metabolic disease, animal models, genetic endocrine disease, cellular endocrinology, protein expression
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.