About this Research Topic
Monitoring and identification of infections is an important issue for diagnosis and therapy, as well as the development of new drugs that can be applied to the clinical stage. In this aspect, fluorescence-based tools have been considered as a powerful tool for the identification and visualization of infection due to its impressive features, including simple operation, high sensitivity and selectivity, and high practical applicability. Identification and visualization of infection via Fluorogenic probes are in its early stages. We are in great need of designing and synthesizing new and novel fluorogenic probes.
The goal of this Research Topic is the development of new fluorogenic probes for the identification and visualization of infections, including gram-negative/positive bacteria, multidrug-resistant bacteria, and viruses. Monitoring of infection biomarkers, as well as structural features of bacteria and viruses, could be a promising target for the identification and visualization of infection. We would like to cover recent research trends and breakthroughs in the development of new sensing concepts and synthesis of fluorogenic probes with practical applications based on small molecular probes, nanoprobes, and devices, for the identification and visualization (one-/two-photon microscopy imaging, photoacoustic imaging, etc.) of infections. Parallel to this, the development of new instrumental methods and theoretical studies based on the fluorescence will be covered. We are also interested to cover fluorogenic sensing of enzymes that cause multidrug resistance of bacteria and surface-proteins that facilitate host-cell fusion of viruses.
We welcome submissions of Original Research, Review, Minireview and Perspective articles. Areas to be covered in this Research Topic may include, but are not limited to:
• Design and synthesis of fluorogenic probes for infection, including bacteria and virus
• Design and synthesis of fluorogenic probes for infection biomarkers
• Identification and visualization techniques of infection
• Synthesis of fluorogenic molecular probes
• Development of fluorogenic Nanoprobes
• Development of fluorogenic devices for infection identification
Keywords: Fluorogenic Probes, Infection, Visualization
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