Research Topic

Non-Pharmacological Management of Fibrosing Interstitial Pulmonary Diseases

About this Research Topic

This Research Topic will address the latest scientific advances in pulmonary rehabilitation and non-pharmacological management strategies for patients suffering from interstitial lung diseases (ILDs), updated to the improved outcomes and survival, and the efficacy of pharmacological treatments and transplantation strategies.
The physiological basis of exercise training effectiveness will be analyzed, defining the most appropriate training strategies and outcome measures of Pulmonary Rehabilitation (PR) in these subjects.
All other relevant non-pharmacological interventions (i.e.: oxygen therapy, dyspnoea and cough management, acute care of exacerbations, and palliation, psychological intervention) aimed to minimize the impact of ILDs on patients, families, and carers will be addressed as well.
Practical recommendations will be provided for a multidisciplinary approach to the patients suffering from ILDs. Particular attention will be dedicated to the burden of fibrotic lung disease following SARS-CoV-2 infection and the role of telehealth and telerehabilitation in non-pharmacological management of fibrosing ILDs in the SARS-CoV-2 era.

Despite the availability of new pharmacological therapies, people with fibrosing ILDs experience reduced functional capacity and distressing symptoms. The current Research Topic aims to cover promising, recent, and novel research trends in non-pharmacological management of interstitial and rare pulmonary diseases.

Areas to be covered in this Research Topic may include, but are not limited to:

1) Pharmacological and non-pharmacological management of ILDs (Review, Mini-review, Original Research)
update of pharmacological and non-pharmacological treatment strategies
new options available for the management of patients suffering from ILDs
fibrotic lung disease following SARS-CoV-2 infection
Physiological basis and evidence supporting exercise training in ILDs
current evidence on oxygen supplementation
The burden of ILDs on patients, families, and carers

2) Multi-professional and multi-dimensional assessment of ILDs patients: current evidence and controversies (Review, Original Research)
Determinants of the lung functional decline
Physiology of ventilatory restriction and impairment of gas exchange
Determinants of exertional hypoxemia, dyspnoea, and functional limitation
determinants of fatigue (deconditioning, poor sleep, comorbidities, hypoxia, dyspnoea, and
psychological distress)
Impact of ILDs symptoms (cough, dyspnoea, exercise limitation, fatigue) on quality of life
Frailty in ILDs
Anxiety, depression, and emotional well-being
The burden of fibrotic lung disease following SARS-CoV-2 infection

3) Multidisciplinary rehabilitation in ILDs. How to build a comprehensive PR program (Review, Original Research)
outcome measures of non-pharmacological interventions in ILDs
refractory dyspnoea and dyspnoea management in ILD
Dedicated exercise training strategies and modalities
Setting and format of Pulmonary Rehabilitation
Key aspects of exercise prescription
Oxygen supplementation in daily life activities and during exercise
Rehabilitation and lung transplantation
Ambulatory oxygen and nocturnal oxygen
Cough: impact and management strategies
Self-management and education for people with ILD

4) Symptom relief and quality of life: from supportive measures to the end-of-life care (Review, Original Research)
Barriers to the development and delivery of Supportive Care
Delivering Disease Education and Psychosocial Support
Role of telehealth and telerehabilitation
Palliative care/supportive care
End-of-life care


Keywords: Non-Pharmacological, Interstitial Lung Disease, Pulmonary Rehabilitation, Pulmonary Fibrosis, Pulmonary Rare Diseases


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

This Research Topic will address the latest scientific advances in pulmonary rehabilitation and non-pharmacological management strategies for patients suffering from interstitial lung diseases (ILDs), updated to the improved outcomes and survival, and the efficacy of pharmacological treatments and transplantation strategies.
The physiological basis of exercise training effectiveness will be analyzed, defining the most appropriate training strategies and outcome measures of Pulmonary Rehabilitation (PR) in these subjects.
All other relevant non-pharmacological interventions (i.e.: oxygen therapy, dyspnoea and cough management, acute care of exacerbations, and palliation, psychological intervention) aimed to minimize the impact of ILDs on patients, families, and carers will be addressed as well.
Practical recommendations will be provided for a multidisciplinary approach to the patients suffering from ILDs. Particular attention will be dedicated to the burden of fibrotic lung disease following SARS-CoV-2 infection and the role of telehealth and telerehabilitation in non-pharmacological management of fibrosing ILDs in the SARS-CoV-2 era.

Despite the availability of new pharmacological therapies, people with fibrosing ILDs experience reduced functional capacity and distressing symptoms. The current Research Topic aims to cover promising, recent, and novel research trends in non-pharmacological management of interstitial and rare pulmonary diseases.

Areas to be covered in this Research Topic may include, but are not limited to:

1) Pharmacological and non-pharmacological management of ILDs (Review, Mini-review, Original Research)
update of pharmacological and non-pharmacological treatment strategies
new options available for the management of patients suffering from ILDs
fibrotic lung disease following SARS-CoV-2 infection
Physiological basis and evidence supporting exercise training in ILDs
current evidence on oxygen supplementation
The burden of ILDs on patients, families, and carers

2) Multi-professional and multi-dimensional assessment of ILDs patients: current evidence and controversies (Review, Original Research)
Determinants of the lung functional decline
Physiology of ventilatory restriction and impairment of gas exchange
Determinants of exertional hypoxemia, dyspnoea, and functional limitation
determinants of fatigue (deconditioning, poor sleep, comorbidities, hypoxia, dyspnoea, and
psychological distress)
Impact of ILDs symptoms (cough, dyspnoea, exercise limitation, fatigue) on quality of life
Frailty in ILDs
Anxiety, depression, and emotional well-being
The burden of fibrotic lung disease following SARS-CoV-2 infection

3) Multidisciplinary rehabilitation in ILDs. How to build a comprehensive PR program (Review, Original Research)
outcome measures of non-pharmacological interventions in ILDs
refractory dyspnoea and dyspnoea management in ILD
Dedicated exercise training strategies and modalities
Setting and format of Pulmonary Rehabilitation
Key aspects of exercise prescription
Oxygen supplementation in daily life activities and during exercise
Rehabilitation and lung transplantation
Ambulatory oxygen and nocturnal oxygen
Cough: impact and management strategies
Self-management and education for people with ILD

4) Symptom relief and quality of life: from supportive measures to the end-of-life care (Review, Original Research)
Barriers to the development and delivery of Supportive Care
Delivering Disease Education and Psychosocial Support
Role of telehealth and telerehabilitation
Palliative care/supportive care
End-of-life care


Keywords: Non-Pharmacological, Interstitial Lung Disease, Pulmonary Rehabilitation, Pulmonary Fibrosis, Pulmonary Rare Diseases


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

17 January 2021 Abstract
16 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

17 January 2021 Abstract
16 May 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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