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Analysis of human genome variation may focus on one of two possible goals: understanding the genome region under study or solving historical and evolutionary questions specific to the population(s) analyzed. Y chromosomal single nucleotide polymorphisms (Y-SNPs), which mutate at a relatively low rate, are ...

Analysis of human genome variation may focus on one of two possible goals: understanding the genome region under study or solving historical and evolutionary questions specific to the population(s) analyzed. Y chromosomal single nucleotide polymorphisms (Y-SNPs), which mutate at a relatively low rate, are usually utilized to trace back human origins and diverse dispersal routes, while Y chromosomal short tandem repeats (Y-STRs) are used in forensics, evolutionary studies, and genealogical analysis to date historical divergent events.

The Y chromosome SNPs/STRs panels are used for forensic, evolutionary studies and genealogical analysis that provides information for human identification, relationship testing, ancestry identification, etc. Scientists have suggested separation of Y-STR loci into two groups, slowly mutating vs. rapidly mutating, which may make results easier to interpret. Few have proposed mixing these STRs and SNPs in a single panel, which can serve all purposes at once.

This Research Topic will give exclusive insight into this ongoing debated of slowly mutating Y-STRs vs. rapidly mutating Y-STRs and inclusion of both SNPs and STRs for evolutionary and population genetics applications.

Keywords: Ancient DNA, SNPs, STRs, Forensic, Polymorphism


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