Research Topic

State of the Art Diagnostic Tools to Study the Origin, Development, and Growth of Cerebral Aneurysms

About this Research Topic

Cerebral aneurysm occur in 3–5% of the general population and are characterized by localized structural deterioration of the arterial wall, with loss of internal elastic lamina and disruption of the media. Cerebral aneurysm wall inflammation has been thought as one of the crucial factors of aneurysm development and growth, and also showed an association with cerebral wall instability. Innovative radiological diagnosis using vessel wall imaging can differentiate cerebral aneurysms with a risk of rupture from stable ones, and can also localize a rupture focus among multiple cerebral aneurysms. Additionally, ultra-high spatial resolution MRI was found to be capable of showing the microstructure of the thrombosed cerebral aneurysm wall. Therefore, these innovative radiological diagnostic techniques are expected to better explain aneurysm pathophysiology.

This Research Topic aims at providing a comprehensive and state-of-the-art coverage of the topic and of its latest advances. Topic Editors invite researchers in the field of cerebral aneurysms to submit their research on recent breakthroughs in implementing novel diagnostic neuroimaging techniques in cerebral aneurysm pathophysiology studies, and in its implementation in the management and follow-up. Additionally, we welcome manuscripts involving advanced neuroimaging techniques, especially but not exclusively cerebral aneurysm vessel wall imaging, and its advanced assessment using ultra-high spatial resolution MRI such as 7 Tesla MRI. Finally, we welcome contributions reporting on developments of various intraoperative adjuncts for cerebral aneurysms management, including advanced neurophysiological monitoring and fluorescence angiography.

Topic Editors welcome contributions on, but not limited to:
• Cerebral aneurysms pathophysiology with focus on origin, development and growth
• Newly developed diagnostic tools, including the application of ultra-high magnetic field MRI
• Newly developed neuroimaging techniques to prevent postoperative complications
• Diagnosis of complex cerebral aneurysms
• Advances and usefulness of various intraoperative monitoring and diagnostic adjuncts


Keywords: cerebral aneurysm, neuroimaging, intraopearative adjunct, radiological diagnosis, MRI


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Cerebral aneurysm occur in 3–5% of the general population and are characterized by localized structural deterioration of the arterial wall, with loss of internal elastic lamina and disruption of the media. Cerebral aneurysm wall inflammation has been thought as one of the crucial factors of aneurysm development and growth, and also showed an association with cerebral wall instability. Innovative radiological diagnosis using vessel wall imaging can differentiate cerebral aneurysms with a risk of rupture from stable ones, and can also localize a rupture focus among multiple cerebral aneurysms. Additionally, ultra-high spatial resolution MRI was found to be capable of showing the microstructure of the thrombosed cerebral aneurysm wall. Therefore, these innovative radiological diagnostic techniques are expected to better explain aneurysm pathophysiology.

This Research Topic aims at providing a comprehensive and state-of-the-art coverage of the topic and of its latest advances. Topic Editors invite researchers in the field of cerebral aneurysms to submit their research on recent breakthroughs in implementing novel diagnostic neuroimaging techniques in cerebral aneurysm pathophysiology studies, and in its implementation in the management and follow-up. Additionally, we welcome manuscripts involving advanced neuroimaging techniques, especially but not exclusively cerebral aneurysm vessel wall imaging, and its advanced assessment using ultra-high spatial resolution MRI such as 7 Tesla MRI. Finally, we welcome contributions reporting on developments of various intraoperative adjuncts for cerebral aneurysms management, including advanced neurophysiological monitoring and fluorescence angiography.

Topic Editors welcome contributions on, but not limited to:
• Cerebral aneurysms pathophysiology with focus on origin, development and growth
• Newly developed diagnostic tools, including the application of ultra-high magnetic field MRI
• Newly developed neuroimaging techniques to prevent postoperative complications
• Diagnosis of complex cerebral aneurysms
• Advances and usefulness of various intraoperative monitoring and diagnostic adjuncts


Keywords: cerebral aneurysm, neuroimaging, intraopearative adjunct, radiological diagnosis, MRI


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

11 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

11 July 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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