About this Research Topic
Single-cell sequencing has emerged as a powerful tool for investigating cell states and functions at the single-cell level. It has greatly revolutionized transcriptomic and epigenomic studies in many life science research fields, including neurobiology and developmental biology. With the fast development of both experimental platforms and bioinformatics approaches over the past decade, single-cell sequencing is becoming economically feasible and experimentally practical for many biomedical laboratories.
The recent application of single-cell sequencing methods to neuroscience has led to a number of exciting discoveries, including classifying neuronal types, discovering new cell types, identifying critical genes underlying brain development and aging and so on. Our research topic here will focus on the combination of single-cell sequencing, including genomics, transcriptomics and epigenomics, and functional exploration of brain development and brain aging and diseases. We welcome original research articles, clinical research articles, as well as review papers related to our topic. Authors will be offered the opportunity to present highlights of their work on an online video platform.
Keywords: single-cell sequencing, neuroscience, neurodevelopment, brain aging
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