The notion that acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome is a ubiquitous finding as old as the concept of ARDS itself, contributing substantially to the complexity of its management. Mechanical ventilation is used to sustain life in patients with ARDS. A major concern in mechanically ventilated patients is the risk of ventilator-induced lung injury, which is partially prevented by lung-protective ventilation.
The COVID-19 pandemic has seen a surge of patients with ARDS in intensive care units across the globe. Although early reports suggested that COVID-19-associated ARDS has distinctive features that set it apart from historical ARDS, emerging evidence indicates that the respiratory system mechanics of patients with ARDS, with or without COVID-19, are broadly similar. Personalised lung-protective mechanical ventilation has become the mainstay of treatment in ARDS. However, prospective evidence, definitions and skills all need to be developed further and shared for better implement of personalised mechanical ventilation in ARDS patients with and without COVID-19.
In this Research Topic, we aim to provide an overview of recent progress in ARDS and mechanical ventilation and seek innovative solutions to resolve the challenges of personalised lung-protective and diaphragm-protective ventilation.
Submissions on, but not limited to, the topics below are welcomed in this collection in the type of Original Article, Review and Mini Review:
- Non-invasive respiratory support for acute respiratory failure
- Mechanical ventilation for patient with and without ARDS
- Advances in diagnosis and treatment of patients with ARDS
- Diaphragmatic function during mechanical ventilation
The notion that acute respiratory distress syndrome (ARDS) is a heterogeneous syndrome is a ubiquitous finding as old as the concept of ARDS itself, contributing substantially to the complexity of its management. Mechanical ventilation is used to sustain life in patients with ARDS. A major concern in mechanically ventilated patients is the risk of ventilator-induced lung injury, which is partially prevented by lung-protective ventilation.
The COVID-19 pandemic has seen a surge of patients with ARDS in intensive care units across the globe. Although early reports suggested that COVID-19-associated ARDS has distinctive features that set it apart from historical ARDS, emerging evidence indicates that the respiratory system mechanics of patients with ARDS, with or without COVID-19, are broadly similar. Personalised lung-protective mechanical ventilation has become the mainstay of treatment in ARDS. However, prospective evidence, definitions and skills all need to be developed further and shared for better implement of personalised mechanical ventilation in ARDS patients with and without COVID-19.
In this Research Topic, we aim to provide an overview of recent progress in ARDS and mechanical ventilation and seek innovative solutions to resolve the challenges of personalised lung-protective and diaphragm-protective ventilation.
Submissions on, but not limited to, the topics below are welcomed in this collection in the type of Original Article, Review and Mini Review:
- Non-invasive respiratory support for acute respiratory failure
- Mechanical ventilation for patient with and without ARDS
- Advances in diagnosis and treatment of patients with ARDS
- Diaphragmatic function during mechanical ventilation