About this Research Topic
Electrospinning is a versatile technique that produces polymeric non-woven fiber mats, principally used for tissue engineering/regeneration, as the fiber mats constitute a 3D environment that has been shown to be beneficial for cells. In addition, the possibility to functionalize the fibers with bioactive compounds results in wider application options. For example, electrospun fibers are excellent drug release systems. In this case, bioactive compounds encapsulated in the fibers are slowly released, often in a tailored manner. Fiber mats can also be functionalized with bioactive compounds after their fabrication, in a post-fabrication step. The functionalization of electrospun fiber mats with bioactive compounds has also led to applications in food packaging, where fiber mats rendered antioxidant, antibacterial, and even releasing bio-agents, can be used for food protection and extending shelf life of foodstuffs.
This Research Topic will cover the different applications of electrospun fiber mats. Firstly, electrospun fibers present a 3D environment for cell culture, which has been shown to be highly beneficial, as they provide in vitro the 3D environment cells encounter in vivo. Secondly, the functionalization of fibers with bioactive compounds provides functionalities that can be used in tissue regeneration, for example in treating burns. Finally, a new potential application investigated recently, in food packaging: the capabilities of the fiber mats to carry bioactive compounds that are either released or impart antibacterial and/or antioxidant properties to the fiber mats, can be used for the development of fiber coatings that can be used in smart packaging.
This Research Topic will explore the investigation of the latest research towards these applications, using the electrospinning technique, either from solution, or melt.
This Research Topic is open to original articles or reviews on the functionalization of electrospun non-woven mats with bioactive compounds for different applications. Themes of interest include, but are not limited to, the following:
· Functional non-woven mats for packaging applications: functionalized with bioactive compounds for antibacterial/antioxidant protection towards smart packaging
· Functional non-woven mats in tissue engineering
· Drug delivery and release from electrospun fibers functionalized with bioactive compounds
· Co-axial electrospinning for drug encapsulation
Keywords: electrospinning, food packaging, drug release, biomaterials, tissue engineering
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.