About this Research Topic
Obesity, a major risk factor for type 2 diabetes, has become a global epidemic and represents an urgent research and medical topic. Rates of overweight and obesity continue to grow both in adults and children. Importantly, according to the concept of fetal programing, the development of obesity has an origin very early in life, in utero, as a result of metabolic or nutrient stress in pregnant mothers. Moreover, the fetal origin of adult diseases theory implicates the contribution of early environment in the womb to the development of various diseases such as cardiovascular disease and diabetes in later life. Finally, the current pandemic of COVID-19 may further aggravate the obesity problem due to lock downs, remote working/schooling, more sedentary style of living, reduced physical activity and increased consumption of unhealthy diet. Thus, obesity is also a major societal challenge, which requires a multidisciplinary approach.
The proposal aims to cover variety of aspects of obesity (from basic science, through clinical studies to treatment and intervention approaches). This proposal will address the developmental origins of this disease during prenatal period of pregnancy, in accordance with the fetal programming concept. It will also focus on sexual dimorphic effects of maternal diets during pregnancy in the offspring. The overall objective of the current. Research Topic is to give an overview of the current advances in the field of obesity research the epidemiological perspective, medical complications, and their economic consequences to basic science in search for intervention and treatment strategies will be addressed.
Area of obesity research cover a variety of topics from basic molecular and cellular research through to clinical research. We focus on the following topics: 1) fetal programming of obesity, 2) sexual dimorphic effects of obesity, and 3) interventions and treatment strategies in children. Thus, the list of themes is broad and outstanding contributions in any domain of obesity are needed. Research papers, case reports, trials and review are welcome, but all must offer new insights, critical or novel perspectives in the field. We thrive to achieve an impact on the global agenda of obesity.
Keywords: Obesity, Diabetes, Metabolism, Brain, Digestive System
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