Research Topic

Malaria Immunology

About this Research Topic

Despite the slight reduction in cases seen in parts of Africa over the last few years, malaria remains a major global health challenge. A combination of the emergence of parasite resistance to most of the available antimalarial drugs and mosquito resistance to insecticides poses a serious threat to malaria control. While a vaccine would be a cost-effective addition to the malaria control armamentarium, the most effective vaccine today is only about 50% effective. There is, therefore, a strong impetus to continue hunting for more effective malaria vaccines. A major hurdle to malaria vaccine development has been the inability to define clear correlates of protective immunity. Malaria infection provokes a wide range of immune responses due to the biological complexity of the malaria parasite and its life cycle. Distinguishing between protective and non-protective responses within this complex immunological milieu remains the main challenge for malaria immunology researchers. This collection is aimed at expanding our understanding of immunity to malaria by collating the latest research in this field.


Keywords: malaria immunology, malaria vaccine, malaria, vaccine development, immunology


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Despite the slight reduction in cases seen in parts of Africa over the last few years, malaria remains a major global health challenge. A combination of the emergence of parasite resistance to most of the available antimalarial drugs and mosquito resistance to insecticides poses a serious threat to malaria control. While a vaccine would be a cost-effective addition to the malaria control armamentarium, the most effective vaccine today is only about 50% effective. There is, therefore, a strong impetus to continue hunting for more effective malaria vaccines. A major hurdle to malaria vaccine development has been the inability to define clear correlates of protective immunity. Malaria infection provokes a wide range of immune responses due to the biological complexity of the malaria parasite and its life cycle. Distinguishing between protective and non-protective responses within this complex immunological milieu remains the main challenge for malaria immunology researchers. This collection is aimed at expanding our understanding of immunity to malaria by collating the latest research in this field.


Keywords: malaria immunology, malaria vaccine, malaria, vaccine development, immunology


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

17 August 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

17 August 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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