About this Research Topic
Clinical and experimental models of respiratory allergic diseases have enabled researchers to assess and characterize new therapies' pharmacological properties under regulated and controlled allergen exposure and conditions. Beyond therapeutic development, these models, including (but not limited to) controlled allergen challenge facilities (CACFs) and direct nasal allergen challenges (NAC,) can be applied to report clinical and physiological disease manifestations, understand disease genomics, epigenetics, the microbiome, and other'-omic' sciences. Insights from such 'big data' outcomes gained from relevant disease models may pave the future for personalized approaches to managing and treating respiratory allergic diseases.
We encourage submissions to this Research Topic on the following themes investigated using experimental models of respiratory allergic diseases:
- Genetics and Epigenetics
- Air pollution and its impact on allergic disease
- Omics Sciences
- Birth Cohorts
Keywords: experimental models, respiratory allergic disease, controlled allergen exposure, CACFs, NAC, disease models
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