About this Research Topic
Neuropathology of the central nervous system (CNS), the meninges, and the peripheral
nerves/peripheral nervous system (PNS) has been assessed by means of histochemistry, enzyme histochemistry and immunohistochemistry (IHC)/immunotargeting for many decades. Although considered standard procedures, these research tools have been continuously keeping up with the most innovative cutting-edge applications by maintaining their reputation and accuracy.
However, neuropathological assessments, histopathology, and IHC are time-consuming and require expertise for generating reliable data. With this Research Topic, we would like to encourage not only experts but also enthusiasts to invest in these highly accurate and attractive applications when presenting their research data and to share recent innovations in these techniques.
Disease mechanisms underlying autoimmune-mediated inflammatory demyelination of the CNS and PNS are still largely unknown. This Research Topic welcomes manuscripts (Original Research, Brief Reports, etc.) that include neuropathological assessments of diseases, and the respective animal models, characterized by autoimmune-mediated inflammatory demyelination. These include diseases such as Multiple Sclerosis (MS), Guillain-Barré syndrome (GBS), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Multifocal Motor Neuropathy (MMN) and Paraproteinaemic Demyelinating Neuropathy (PDN).
We also welcome submissions of Review Articles, which should address historical development and current state-of-the-art of the application of neuropathological assessment in research studies, as well as reflections on its relevance and accuracy.
Topic Editor Sonja Hochmeister received financial support from Fresenius-Kabi, Roche-Genentech and Merck. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
nerves/peripheral nervous system (PNS) has been assessed by means of histochemistry, enzyme histochemistry and immunohistochemistry (IHC)/immunotargeting for many decades. Although considered standard procedures, these research tools have been continuously keeping up with the most innovative cutting-edge applications by maintaining their reputation and accuracy.
However, neuropathological assessments, histopathology, and IHC are time-consuming and require expertise for generating reliable data. With this Research Topic, we would like to encourage not only experts but also enthusiasts to invest in these highly accurate and attractive applications when presenting their research data and to share recent innovations in these techniques.
Disease mechanisms underlying autoimmune-mediated inflammatory demyelination of the CNS and PNS are still largely unknown. This Research Topic welcomes manuscripts (Original Research, Brief Reports, etc.) that include neuropathological assessments of diseases, and the respective animal models, characterized by autoimmune-mediated inflammatory demyelination. These include diseases such as Multiple Sclerosis (MS), Guillain-Barré syndrome (GBS), Chronic Inflammatory Demyelinating Polyneuropathy (CIDP), Multifocal Motor Neuropathy (MMN) and Paraproteinaemic Demyelinating Neuropathy (PDN).
We also welcome submissions of Review Articles, which should address historical development and current state-of-the-art of the application of neuropathological assessment in research studies, as well as reflections on its relevance and accuracy.
Topic Editor Sonja Hochmeister received financial support from Fresenius-Kabi, Roche-Genentech and Merck. The other Topic Editors declare no competing interests with regard to the Research Topic subject.
Keywords: MS, GBS, CIPD, autoimmune neuroinflammation, demyelination
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
