About this Research Topic
Tissue Engineering is an emerging multidisciplinary field of research, aiming at designing appropriate systems, platforms or technologies that can lead to (i) the development of healthy or diseased tissue equivalents to be used as models for studying tissue evolution and response to medical treatments (ii) the development of appropriate biodegradable models that can be used for tissue healing and regeneration in vivo (via implantation) (iii) the delivery of therapies at specific locations of the body in a targeted manner.
The aim of this research topic is to discuss chemical engineering related advances in the field of tissue engineering, regenerative medicine and cell therapies. Furthermore, the approach can be experimental, computational or hybrid. Over the last decades, tissue engineering and regenerative medicine has moved from fundamental research to the development of successful products to the market. Processes involved for the success of such products may involve smart biomaterials, novel microfluidic devices, bioreactors etc. All such technologies vary in scale from nano to macro and large scale, and contribute to the successful and robust production of such novel ‘living products’. Therefore, the goal of this research topic is to discuss the state-of-the art in this progressively maturing multidisciplinary domain.
Topics covered by this Research Topic include, but are not limited to:
• Biomaterials for tissue scaffold fabrication and design.
• Bioreactor design with focus on tissue mimicry and regeneration (both for healthy or diseased systems).
• Stem cell engineering, e.g., 3D or microfluidic platforms for stem cell culture and scale up, molecular and physical cue in stem cell differentiation and reprogramming.
• Exosome production.
• In silico approaches in tissue engineering design.
• Automation in Tissue Engineering and cell therapies.
• Drug and Biomolecule Delivery systems.
• In vivo applications and/or validations of technologies.
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.