Research Topic

Nanobiotechnology Enabled Point-of-Care Devices

About this Research Topic

Over the years, there are increasing needs for the development of simple, cost-effective, portable, integrated biosensors that can be operated outside the laboratory by untrained personnel. Maximum conventional enzyme-based biosensors suffer from low signal amplification and complicated detection protocol.

Signal amplification is an important tool for accurate measurement of biomarkers in their very early stage. In this topic, the challenges for the development of a point-of-care test platform for early-stage diseases detection in serum or blood (also noninvasive testing in saliva, sweat, or in urine) describing fundamental aspects, developments, and their contribution to the area of biosensor relating relevant aspects of the development of sensors will be highlighted. The main goal of this topic is to use the fundamental knowledge of signal amplification and printed electronics in a portable device for simple and effective point-of-care testing for early-stage disease diagnosis before the extreme stage and can save the patient life.

In this proposal, we address the challenges for the development of a point-of-care-test platform. The proposal also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, biomarkers detection in real samples. The main challenges of point-of-care testing require implementing complex analytical methods into low-cost technologies. This is particularly true for countries with less developed health care infrastructure. Washing-free, Lab-on-Chip, Lab-on-PCB techniques are very simple and innovative for point-of-care device development. The redox cycling technology will detect several interesting targets at the same time on a printed chip. The proposed areas are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics & electrical engineering, healthcare, and manufacturing.

• Major challenges for the development of next-generation point-of-care-test platform.
• Advances in Lab-on-Chip technology for biomarker detection
• Nanobiotechnology-based biosensors for healthcare systems.
• Biosensor signal amplification strategies for early-stage disease detection
• Design of biodevices for COVID-19 Diagnosis in a rural health care setting
• Cancer diagnosis based on nanobiotechnology enabled biodevices.
• Micro Total Analysis Systems (µTAS) for device development.
• Integration of biosensors with fuel cell for self-powered biodevices


Keywords: nanobiotechnology, Lab-on-a-Chip, Microfluidics, Point-of-Care devices, biosensors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Over the years, there are increasing needs for the development of simple, cost-effective, portable, integrated biosensors that can be operated outside the laboratory by untrained personnel. Maximum conventional enzyme-based biosensors suffer from low signal amplification and complicated detection protocol.

Signal amplification is an important tool for accurate measurement of biomarkers in their very early stage. In this topic, the challenges for the development of a point-of-care test platform for early-stage diseases detection in serum or blood (also noninvasive testing in saliva, sweat, or in urine) describing fundamental aspects, developments, and their contribution to the area of biosensor relating relevant aspects of the development of sensors will be highlighted. The main goal of this topic is to use the fundamental knowledge of signal amplification and printed electronics in a portable device for simple and effective point-of-care testing for early-stage disease diagnosis before the extreme stage and can save the patient life.

In this proposal, we address the challenges for the development of a point-of-care-test platform. The proposal also describes printed chip-based assay (Lab-on-a-Chip, Lab-on-a-PCB) for rapid, inexpensive, biomarkers detection in real samples. The main challenges of point-of-care testing require implementing complex analytical methods into low-cost technologies. This is particularly true for countries with less developed health care infrastructure. Washing-free, Lab-on-Chip, Lab-on-PCB techniques are very simple and innovative for point-of-care device development. The redox cycling technology will detect several interesting targets at the same time on a printed chip. The proposed areas are inherently cross-disciplinary, combining expertise in biosensing, electrochemistry, electronics & electrical engineering, healthcare, and manufacturing.

• Major challenges for the development of next-generation point-of-care-test platform.
• Advances in Lab-on-Chip technology for biomarker detection
• Nanobiotechnology-based biosensors for healthcare systems.
• Biosensor signal amplification strategies for early-stage disease detection
• Design of biodevices for COVID-19 Diagnosis in a rural health care setting
• Cancer diagnosis based on nanobiotechnology enabled biodevices.
• Micro Total Analysis Systems (µTAS) for device development.
• Integration of biosensors with fuel cell for self-powered biodevices


Keywords: nanobiotechnology, Lab-on-a-Chip, Microfluidics, Point-of-Care devices, biosensors


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

07 June 2021 Abstract
05 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..

Topic Editors

Loading..

Submission Deadlines

07 June 2021 Abstract
05 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..