About this Research Topic
Skin aging is the most direct manifestation of human aging. Skin is directly in contact with the outside and is stimulated by various external factors, such as UV radiations, microorganisms, etc. External and internal stimuli can trigger the immune response of skin cells, causing a series of inflammatory reactions, which can induce skin diseases such as psoriasis, rosacea, atopic dermatitis, etc. Moreover, long-term repeated inflammation may induce skin cells senescence. Aging also influences the activity of stem cells and wound responses. Therefore, a deep understanding of inflammation, stem cell response and wound healing in skin aging is needed to help advance the regenerative biology field and future clinical applications.
To advance our understanding of inflammation, regulation of stem cells and wound response during skin aging, we need to know:
1) How skin cells inflammation is regulated in the senescence process.
2) How skin stem cells fate is regulated during skin aging.
3) How the skin wound repair and regeneration are regulated during skin aging.
4) The pathogenesis of inflammatory dermatosis, such as psoriasis, atopic dermatitis, rosacea, etc.
5) Other possible mechanisms of skin aging.
The aim of the current Research Topic is to cover recent, promising, and novel research trends in inflammation, stem cells and wound healing in skin aging. Areas to be covered in this Research Topic may include, but are not limited to:
• Immune cell response in the skin, including response to foreign antigens, self-antigens, and commensal microbes;
• Regulation of skin cells in the inflammatory process;
• Inflammatory dermatosis, such as psoriasis, rosacea, etc.;
• Skin inflammation and aging;
• Regeneration of skin and appendages;
• Stem cell behavior in the skin aging;
• Repair and regeneration during wound healing;
• Canceration during skin aging.
To advance our understanding of inflammation, regulation of stem cells and wound response during skin aging, we need to know:
1) How skin cells inflammation is regulated in the senescence process.
2) How skin stem cells fate is regulated during skin aging.
3) How the skin wound repair and regeneration are regulated during skin aging.
4) The pathogenesis of inflammatory dermatosis, such as psoriasis, atopic dermatitis, rosacea, etc.
5) Other possible mechanisms of skin aging.
The aim of the current Research Topic is to cover recent, promising, and novel research trends in inflammation, stem cells and wound healing in skin aging. Areas to be covered in this Research Topic may include, but are not limited to:
• Immune cell response in the skin, including response to foreign antigens, self-antigens, and commensal microbes;
• Regulation of skin cells in the inflammatory process;
• Inflammatory dermatosis, such as psoriasis, rosacea, etc.;
• Skin inflammation and aging;
• Regeneration of skin and appendages;
• Stem cell behavior in the skin aging;
• Repair and regeneration during wound healing;
• Canceration during skin aging.
Keywords: skin inflammation, aging, dermatosis, wound healing, skin stem cells
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
