Research Topic

Salivary Gland Tumors: Epidemiology, Pathology, Molecular Genetics, Management and Future Directions

About this Research Topic

Morphologic and molecular heterogeneity of salivary gland tumors (SGTs) has resulted in ever-changing classification and reclassification of many entities over the decades, in addition to description of new tumors. Recent advances offer new molecular diagnostic techniques to help differentiate SGTs, particularly malignant tumors, with the obvious benefit of improvement in diagnosis as well as improved management outcomes. Every new piece of knowledge about SGTs underlines our incomplete understanding of these tumors.

The objective of this Research Topic is to collate present knowledge of all aspects of SGTs including epidemiology, pathology, molecular genetics, and management. Articles, including original research and reviews, on clinical innovations in SGTs, dissecting future routes that may lead to significant improvements of outcomes through multidisciplinary collaborations and approaches are desired. Studies targeting innovative diagnostic approaches and risk-profile towards personalized treatments are also welcome. Comparative analysis between major and minor SGTs are encouraged, in addition to studies devoted solely to minor glands.

We are particularly interested in receiving papers describing:
• Strategies and new tools for the diagnosis of STGs
• Biological mechanisms underlying tumor initiation and progression
• Characterization and participation of cancer stem cells on therapeutic resistance
• Impact of the tumor microenvironment on tumor progression
• Description of markers for the treatment decision-making and prognosis
• Innovative strategies on treatment and management of patients


Keywords: Salivary gland tumors, salivary gland cancer, diagnosis, prognosis, therapy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Morphologic and molecular heterogeneity of salivary gland tumors (SGTs) has resulted in ever-changing classification and reclassification of many entities over the decades, in addition to description of new tumors. Recent advances offer new molecular diagnostic techniques to help differentiate SGTs, particularly malignant tumors, with the obvious benefit of improvement in diagnosis as well as improved management outcomes. Every new piece of knowledge about SGTs underlines our incomplete understanding of these tumors.

The objective of this Research Topic is to collate present knowledge of all aspects of SGTs including epidemiology, pathology, molecular genetics, and management. Articles, including original research and reviews, on clinical innovations in SGTs, dissecting future routes that may lead to significant improvements of outcomes through multidisciplinary collaborations and approaches are desired. Studies targeting innovative diagnostic approaches and risk-profile towards personalized treatments are also welcome. Comparative analysis between major and minor SGTs are encouraged, in addition to studies devoted solely to minor glands.

We are particularly interested in receiving papers describing:
• Strategies and new tools for the diagnosis of STGs
• Biological mechanisms underlying tumor initiation and progression
• Characterization and participation of cancer stem cells on therapeutic resistance
• Impact of the tumor microenvironment on tumor progression
• Description of markers for the treatment decision-making and prognosis
• Innovative strategies on treatment and management of patients


Keywords: Salivary gland tumors, salivary gland cancer, diagnosis, prognosis, therapy


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

26 June 2021 Abstract
24 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

26 June 2021 Abstract
24 October 2021 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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