Research Topic

Orofacial Infections: From Pathogenesis to Intervention

About this Research Topic

The clinical spectrum of orofacial infections affecting the skin or mucus membranes of the face and oral cavity is quite diverse, and such infections may be localized and indolent, or invasive and life -threatening. These infections may be conveniently categorized as odontogenic and non-odontogenic. The anatomical and functional complexity of the orofacial region and the presence of contiguous spaces aid spread of infections in the region, making diagnosis sometimes challenging and increasing the potential for severe complications. The spread of infections has been found to follow the path of least resistance through connective tissue and along fascial planes leading to diverse presentations depending on the type, site and area of spread.

Clinical presentation ranges from toothache, limitation of mouth opening, fever, malaise and dysphagia. In their most severe form, orofacial infections can lead to death, which usually results from an acute airway obstruction or multi-organ failure. In the developed world, fatal dental infections are rare in patients with intact immune response, however in the third world where people are generally poor and malnourished, such fatal orofacial infections are common.
The goal of this Research Topic is to provide a comprehensive understanding of orofacial infections, from pathogenesis to intervention. We welcome papers with particular emphasis on:

- Scientific evidence of the epidemiological characteristics of orofacial infections
- Scientific evidence of the microbiological characteristics of orofacial infections
- Scientific evidence of the pathogenesis of orofacial infections
- Scientific evidence supporting standardized management protocols of orofacial infections


Keywords: orofacial infections


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The clinical spectrum of orofacial infections affecting the skin or mucus membranes of the face and oral cavity is quite diverse, and such infections may be localized and indolent, or invasive and life -threatening. These infections may be conveniently categorized as odontogenic and non-odontogenic. The anatomical and functional complexity of the orofacial region and the presence of contiguous spaces aid spread of infections in the region, making diagnosis sometimes challenging and increasing the potential for severe complications. The spread of infections has been found to follow the path of least resistance through connective tissue and along fascial planes leading to diverse presentations depending on the type, site and area of spread.

Clinical presentation ranges from toothache, limitation of mouth opening, fever, malaise and dysphagia. In their most severe form, orofacial infections can lead to death, which usually results from an acute airway obstruction or multi-organ failure. In the developed world, fatal dental infections are rare in patients with intact immune response, however in the third world where people are generally poor and malnourished, such fatal orofacial infections are common.
The goal of this Research Topic is to provide a comprehensive understanding of orofacial infections, from pathogenesis to intervention. We welcome papers with particular emphasis on:

- Scientific evidence of the epidemiological characteristics of orofacial infections
- Scientific evidence of the microbiological characteristics of orofacial infections
- Scientific evidence of the pathogenesis of orofacial infections
- Scientific evidence supporting standardized management protocols of orofacial infections


Keywords: orofacial infections


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

30 November 2021 Abstract
31 March 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

30 November 2021 Abstract
31 March 2022 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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